| Title: |
Incidence of thyroid carcinoma in fluorodeoxyglucose positron emission tomography-positive thyroid incidentalomas. |
| Authors: |
King DL; Stack BC Jr; Spring PM; Walker R; Bodenner DL; King, Deanne L; Stack, Brendan C Jr; Spring, Paul M; Walker, Ronald; Bodenner, Donald L |
| Source: |
Otolaryngology-Head & Neck Surgery; Sep2007, Vol. 137 Issue 3, p400-404, 5p |
| Abstract: |
Objective: Fluorodeoxyglucose (FDG) whole body positron emission tomography (PET) scan may show clinically occult second lesions. Such lesions in the thyroid are increasingly common. There are several recent reports of a high probability of malignancy in these lesions ranging from 14% to 63%. Study Design and Setting: This is a retrospective review of 15,711 PET scans at a multi-disciplinary thyroid clinic at a tertiary care university medical center. Twenty-two patients were referred with thyroid PET "incidentalomas." The review included 18 FDG-PET scans, ultrasound guided fine needle aspiration biopsies, and thyroid surgery pathology. Aspiration cytology or pathology were the main outcome measures. Results: Three patients had malignancy of the PET-positive thyroid lesions. Papillary thyroid micro carcinomas were detected in four of the specimens that showed a benign pathology of the dominant nodule. Conclusion: Our experience shows a 14% malignancy rate for the dominant (imaged) nodule and a total malignancy rate of 32% when the incidental micro carcinomas are included. Both of these rates are significantly lower than results published previously. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |