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Unusual presentation of occult follicular carcinoma of thyroid: As thoracic wall lump.

Title: Unusual presentation of occult follicular carcinoma of thyroid: As thoracic wall lump.
Authors: Nawarathna, Nadeesha J; Kumarasinghe, Navam R.; Chandrasekera, Deepthika N.; Senevirathna, Ranjith J. K.
Source: Thyroid Research & Practice; Jan-Apr2016, Vol. 13 Issue 1, p36-39, 4p
Subject Terms: Thyroid crisis; Thyroid diseases; Thoracic aneurysms; Thyroid cancer treatment; Metastasis; Disease risk factors; Therapeutics
Abstract: Occult thyroid carcinoma presenting with clinically apparent metastasis is rare and is a diagnostic challenge. Here we report a 68-year-old male who presented with a left side chest wall mass of one year duration. The mass showed rapid enlargement at the latter end of its course, following an initial asymptomatic period. Imaging studies showed a soft tissue mass eroding into several ribs. Wide local excision with primary reconstruction was performed. Histological studies and immune staining revealed metastasis from a follicular thyroid carcinoma. Total thyroidectomy followed, confirming the diagnosis. Post-operatively radio isotope ablation (I131) was done. A suppression dose of thyroxin was continued with regular thyroglobulin assays. Painful bone metastasis responded well to analgesics, bisphosphonates and external beam radiotherapy. Follicular carcinoma comprise 10-15% of thyroid malignancies. Localized thyroid carcinoma has a very good prognosis, 10 year survival rates reducing by 50% with metastatic disease. Commonly thyroid cancer presents as detectable thyroid nodules, 25% having metastasis. In contrast metastatic manifestations are reported in less than 5% of occult thyroid cancers. [ABSTRACT FROM AUTHOR]
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Database: Complementary Index