| Title: |
Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells. |
| Authors: |
Weinberger, Florian; Breckwoldt, Kaja; Pecha, Simon; Kelly, Allen; Geertz, Birgit; Starbatty, Jutta; Yorgan, Timur; Kai-Hung Cheng; Lessmann, Katrin; Stolen, Tomas; Scherrer-Crosbie, Marielle; Smith, Godfrey; Reichenspurner, Hermann; Hansen, Arne; Eschenhagen, Thomas |
| Source: |
Science Translational Medicine; 11/2/2016, Vol. 8 Issue 363, p1-12, 12p, 3 Color Photographs, 4 Graphs |
| Subject Terms: |
Heart transplantation; Artificial hearts; Heart cells; Pluripotent stem cells; Cardiac surgery; Endothelial cells; Transplantation of organs, tissues, etc. |
| Abstract: |
The article discusses a study which examined the results of the transplantation of human pluripotent stem cell-derived cardiomyocytes (hiPSC). The study created human engineered heart tissue (hEHT) strips from hiPSC-derived cardiomyocytes and hiPSC-derived endothelial cells. It demonstrated that the hearts repaired with hEHT strips 28 days after their transplantation. |
| Database: |
Complementary Index |