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[Effect of high doses of atorvastatin on the endothelial function of the coronary arteries].

Title: [Effect of high doses of atorvastatin on the endothelial function of the coronary arteries].
Transliterated Title: Dideliu atorvastanino doziu poveikis vainikiniu arteriju endotelio funkcijai.
Authors: Simaitis A; Klaipeda Seamen's Hospital, Vilnius University, Liepojos pl. 45, 5809 Klaipeda, Lithuania. audrsima@takas.lt; Laucevicius A
Source: Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2003; Vol. 39 (1), pp. 21-9.
Publication Type: Comparative Study; Journal Article
Language: Lithuanian
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 9425208 Publication Model: Print Cited Medium: Print ISSN: 1010-660X (Print) Linking ISSN: 1010660X NLM ISO Abbreviation: Medicina (Kaunas) Subsets: MEDLINE
Imprint Name(s): Publication: 2018- : Basel, Switzerland : MDPI; Original Publication: Kaunas : Lietuvos gydytojų sąjunga
MeSH Terms: Anticholesteremic Agents/*administration & dosage ; Coronary Disease/*drug therapy ; Endothelium, Vascular/*drug effects ; Heptanoic Acids/*administration & dosage ; Pyrroles/*administration & dosage; Acetylcholine/administration & dosage ; Cholesterol/blood ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Coronary Disease/blood ; Coronary Disease/physiopathology ; Endothelium, Vascular/physiology ; Lipoproteins, LDL/blood ; Triglycerides/blood ; Adult ; Aged ; Atorvastatin ; Coronary Angiography ; Data Interpretation, Statistical ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Regression Analysis ; Time Factors
Abstract: Objective: The aim of this study is to investigate the role of high doses of atorvastatin (80 mg per day) in the treatment of endothelium dysfunction of the coronary arteries.; Material and Methods: Intracoronary acethylcholine test was performed for 28 (16 in treatment group and 12 in control group) patients who had normal coronary angiogram or minimal lesions (stenosis
Substance Nomenclature: 0 (Anticholesteremic Agents); 0 (Cholesterol, HDL); 0 (Cholesterol, LDL); 0 (Heptanoic Acids); 0 (Lipoproteins, LDL); 0 (Pyrroles); 0 (Triglycerides); 97C5T2UQ7J (Cholesterol); A0JWA85V8F (Atorvastatin); N9YNS0M02X (Acetylcholine)
Entry Date(s): Date Created: 20030211 Date Completed: 20030314 Latest Revision: 20181130
Update Code: 20260130
PMID: 12576762
Database: MEDLINE

Comparative Study; Journal Article