A simple method for determination of surface volume mean diameters of oil in water submicron emulsions.
| Title: | A simple method for determination of surface volume mean diameters of oil in water submicron emulsions. |
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| Authors: | Apte SP; Alcon Research INC., Fort Worth, Texas 76134, USA. shireesh.apte@alconlads.com; Ugwu SO |
| Source: | Die Pharmazie [Pharmazie] 2004 Jul; Vol. 59 (7), pp. 530-3. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Govi-Verlag Pharmazautischer Verlag Country of Publication: Germany NLM ID: 9800766 Publication Model: Print Cited Medium: Print ISSN: 0031-7144 (Print) Linking ISSN: 00317144 NLM ISO Abbreviation: Pharmazie Subsets: MEDLINE |
| Imprint Name(s): | Publication: Eschborn : Govi-Verlag Pharmazautischer Verlag; Original Publication: Berlin, Verlag Dr. W. Saenger, [1946- |
| MeSH Terms: | Emulsions/*chemistry; Latex ; Microspheres ; Nephelometry and Turbidimetry ; Oils ; Particle Size ; Polystyrenes ; Water |
| Abstract: | Plots of the droplet size parameter, alpha = (pi(n)D / lambda) versus the total scattering coefficient or specific turbidity, K, are sinusoidal curves. It was noticed that, along one branch of the K-alpha curve (up to 1.1 microm for relative refractive indices (rr(I)) < 1.2), the wavelength dependence on turbidity; i.e. the extent to which light at different wavelengths is scattered showed a progressive decrease with increase in droplet diameter. It was in fact found that when the logarithm of the relative standard deviations (RSD's) in specific turbidities at four different wavelengths (for a particular droplet diameter and relative refractive index) was plotted as a function of that diameter, a straight line resulted. This relationship provides a valuable new method for estimating the surface volume mean droplet size, D(vs), for submicron emulsions by means of simple spectro-turbidimetry. |
| Substance Nomenclature: | 0 (Emulsions); 0 (Latex); 0 (Oils); 0 (Polystyrenes); 059QF0KO0R (Water) |
| Entry Date(s): | Date Created: 20040807 Date Completed: 20040903 Latest Revision: 20131121 |
| Update Code: | 20260130 |
| PMID: | 15296090 |
| Database: | MEDLINE |
Journal Article