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Cognitive behaviour therapy for adolescents with chronic fatigue syndrome: randomised controlled trial.

Title: Cognitive behaviour therapy for adolescents with chronic fatigue syndrome: randomised controlled trial.
Authors: Stulemeijer M; Expert Centre Chronic Fatigue, University Medical Centre Nijmegen, PO Box 9101, 6500 HB, Netherlands.; de Jong LW; Fiselier TJ; Hoogveld SW; Bleijenberg G
Source: BMJ (Clinical research ed.) [BMJ] 2005 Jan 01; Vol. 330 (7481), pp. 14. Date of Electronic Publication: 2004 Dec 07.
Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Language: English
Journal Info: Publisher: British Medical Association Country of Publication: England NLM ID: 8900488 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-1833 (Electronic) Linking ISSN: 09598138 NLM ISO Abbreviation: BMJ Subsets: MEDLINE
Imprint Name(s): Original Publication: London : British Medical Association
MeSH Terms: Cognitive Behavioral Therapy/*methods ; Fatigue Syndrome, Chronic/*therapy; Absenteeism ; Adolescent ; Child ; Female ; Humans ; Male ; Treatment Outcome
Abstract: Objective: To evaluate the efficacy of cognitive behaviour therapy for adolescents aged 10-17 years with chronic fatigue syndrome.; Design: Randomised controlled trial.; Setting: Department of child psychology.; Participants: 71 consecutively referred patients with chronic fatigue syndrome; 36 were randomly assigned to immediate cognitive behaviour therapy and 35 to the waiting list for therapy.; Intervention: 10 sessions of therapy over five months. Treatment protocols depended on the type of activity pattern (relatively active or passive). All participants were assessed again after five months.; Main Outcome Measures: Fatigue severity (checklist individual strength), functional impairment (SF-36 physical functioning), and school attendance.; Results: 62 patients had complete data at five months (29 in the immediate therapy group and 33 on the waiting list). Patients in the therapy group reported significantly greater decrease in fatigue severity (difference in decrease on checklist individual strength was 14.5, 95% confidence interval 7.4 to 21.6) and functional impairment (difference in increase on SF-36 physical functioning was 17.3, 6.2 to 28.4) and their attendance at school increased significantly (difference in increase in percentage school attendance was 18.2, 0.8 to 35.5). They also reported a significant reduction in several accompanying symptoms. Self reported improvement was largest in the therapy group.; Conclusion: Cognitive behaviour therapy is an effective treatment for chronic fatigue syndrome in adolescents.
Comments: Erratum in: BMJ. 2005 Apr 9;330(7495):820.; Comment in: BMJ. 2005 Apr 2;330(7494):789-90; author reply 790. doi: 10.1136/bmj.330.7494.789-b.. (PMID: 15802727)
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Entry Date(s): Date Created: 20041209 Date Completed: 20050112 Latest Revision: 20220408
Update Code: 20260130
PubMed Central ID: PMC539840
DOI: 10.1136/bmj.38301.587106.63
PMID: 15585538
Database: MEDLINE

Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't