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The Effects of Predictive Factors on Patient Prognosis in the Administration of Medical and Surgical Treatment in Patients with Acute Pancreatitis.

Title: The Effects of Predictive Factors on Patient Prognosis in the Administration of Medical and Surgical Treatment in Patients with Acute Pancreatitis.
Alternate Title: Akut Pankreatitli Hastalarda Medikal ve Cerrahi Tedavi Uygulamasında Prediktif Faktörlerin Hasta Prognozu Üzerine Etkileri. (Turkish)
Authors: Teker, Kenan; Üstün, Mehmet; Yıldırım, Mehmet; Karaali, Cem
Source: Journal of Tepecik Education & Research Hospital / İzmir Tepecik Eğitim ve Araştırma Hastanesi Dergisi; nis2022, Vol. 32 Issue 1, p107-114, 8p
Subject Terms: THERAPEUTICS; DEMOGRAPHIC surveys; PANCREATITIS; CORONARY artery disease; HOSPITALS
Abstract (English): Objective: This study aimed to evaluate the effects of predictive factors on prognosis in medical and surgical treatment practices in patients with acute pancreatitis (AP). Methods: Demographic data, laboratory parameters, co-morbidities, imaging method results, treatment procedures, Ranson Score (RS) and Balthazar Score (BS) of the patients who were diagnosed with AP and followed up and treated between January 2008 and February 2012 were retrospectively analyzed. The patients were divided into two groups as those who underwent medical and surgical treatment, and the effects of predictive factors were evaluated according to the treatment decisions of the patients and their mortality and morbidity during treatment. Results: Coronary artery disease (n=31) as a co-morbidity in the medical treatment group was found to be statistically significant compared to the surgery group (n=2) (p=0.018). In the comparison of RS and related pancreatitis severity between both groups; In the comparison of severe or mild treatment choice, it was found statistically significant that the cases who underwent surgical treatment had mild severity. A statistically significant difference was found between late RS and morbidity and mortality (p=0.037). It was found that as BS increased, mortality increased significantly (p=0.008). The length of hospital stay was significantly shorter in patients who received medical treatment (p=0.001). Conclusion: We found that coronary artery disease and length of hospital stay were more common in medically treated AP patients, and surgically treated patients were mildly severe. Additionally, we found that morbidity and mortality were relaeted with the increase in late RS, and mortality was releated with increase in BS. [ABSTRACT FROM AUTHOR]
Abstract (Turkish): Amaç: Bu çalışmanın amacı akut pankreatit (AP) tanılı hastalarda medikal ve cerrahi tedavi uygulamalarında prediktif faktörlerin prognoz üzerine olan etkilerini araştırmaktır. Yöntem: Ocak 2008 - Şubat 2012 tarihleri arasında AP tanısı konularak takip ve tedavi edilen hastaların demografik verileri, laboratuvar parametreleri, yandaş hastalıkları, görüntüleme yöntem sonuçları, uygulanan tedavi prosedürleri, Ranson Skoru (RS) ve Balthazar Skorları (BS) retrospektif olarak incelendi. Hastalar medikal ve cerrahi tedavi uygulananlar olarak iki gruba ayrılarak hastaların tedavi kararı verilmesinde ve tedavi sırasındaki mortalite ve morbiditelerine göre prediktif faktörlerin etkileri incelendi. Bulgular: Medikal tedavi uygulanan hasta grubunda yandaş hastalık olarak koroner arter hastalığı (n=31) cerrahi uygulanan hasta grubuna göre (n=2) istatistiksel olarak anlamlı saptanmıştır (p=0,018). Her iki grup arasında RS ve buna bağlı belirlenen pankreatit şiddeti karşılaştırmasında; şiddetli veya hafif olmasıyla tedavi seçiminin karşılaştırılmasında cerrahi tedavi uygulanan olguların hafif şiddette olması istatistiksel olarak anlamlı saptandı. Geç RS ile morbidite ve mortalite arasında istatistiksel olarak anlamlı fark saptandı (p=0,037). BS arttıkça mortalitenin arttığı anlamlı olarak bulunmuştur (p=0,008). Medikal tedavi uygulanan hastaların hastanede kalış süresi anlamlı olarak daha kısadır (p=0,001). Sonuç: Yandaş hastalık olarak koroner arter hastalığınınve hastanede yatış süresinin medikal olarak tedavi edilen AP hastalarında daha sık olduğu, cerrahi olarak tedavi edilen hastaların hafif şiddette olanlar olduğunu saptadık. Bunun yanında geç RS'nin artması ile morbidite ve mortalitenin arttığını, BS arttıkça da mortalitenin arttığını saptadık. [ABSTRACT FROM AUTHOR]
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Database: Complementary Index