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Evolution of Clinical-Pathological Correlations in Early-Onset Alzheimer's Disease Over a 25-Year Period in an Academic Brain Bank.

Title: Evolution of Clinical-Pathological Correlations in Early-Onset Alzheimer's Disease Over a 25-Year Period in an Academic Brain Bank.
Authors: Sarto, Jordi; Mayà, Gerard; Molina-Porcel, Laura; Balasa, Mircea; Gelpi, Ellen; Aldecoa, Iban; Borrego-Écija, Sergi; Contador, Jose; Ximelis, Teresa; Vergara, Miguel; Antonell, Anna; Sánchez-Valle, Raquel; Albert, Lladó; Neurological Tissue Bank, Biobanc-Hospital Clínic Barcelona-IDIBAPS Collaborative Group; Lladó, Albert
Source: Journal of Alzheimer's Disease; 2022, Vol. 87 Issue 4, p1659-1669, 11p
Abstract: Background: Early onset Alzheimer's disease (EOAD) represents a diagnostic challenge and is associated with a high diagnostic delay and misdiagnosis.Objective: To describe clinical and pathological data from a pathologically confirmed EOAD cohort and evaluate evolving trends in clinical-pathological correlation accuracy.Methods: Retrospective review of clinical and neuropathological data of pathologically confirmed EOAD patients (age at onset [AAO] 
: Copyright of Journal of Alzheimer's Disease is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Complementary Index