Etiology of bile infection and its association with postoperative complications following pancreatoduodenectomy.
| Title: | Etiology of bile infection and its association with postoperative complications following pancreatoduodenectomy. |
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| Authors: | Grizas S; Clinic of Surgery, Kaunas University of Medicine Hospital, Eiveniu 2, 50009 Kaunas, Lithuania. saulius_grizas@yahoo.co.uk; Stakyte M; Kincius M; Barauskas G; Pundzius J |
| Source: | Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2005; Vol. 41 (5), pp. 386-91. |
| Publication Type: | Comparative Study; Evaluation Study; Journal Article |
| Language: | English |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 9425208 Publication Model: Print Cited Medium: Internet ISSN: 1648-9144 (Electronic) Linking ISSN: 1010660X NLM ISO Abbreviation: Medicina (Kaunas) Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2018- : Basel, Switzerland : MDPI; Original Publication: Kaunas : Lietuvos gydytojų sąjunga |
| MeSH Terms: | Pancreaticoduodenectomy*/adverse effects; Bacterial Infections/*etiology ; Bile/*microbiology ; Postoperative Complications/*etiology; Bacteria/isolation & purification ; Cholangitis/complications ; Pancreatic Neoplasms/surgery ; Surgical Wound Infection/etiology ; Adult ; Aged ; Cholangiopancreatography, Endoscopic Retrograde ; Data Interpretation, Statistical ; Drainage ; Female ; Humans ; Male ; Middle Aged ; Preoperative Care ; Prospective Studies ; Stents |
| Abstract: | Unlabelled: Currently controversy exists whether bile infection following preoperative biliary drainage has an impact on postoperative complications and mortality rate. The objective of the study was to determine etiology of preoperative bile infection and to evaluate its influence on postoperative complications and mortality after pancreatoduodenectomy.; Methods: Data on 64 patients, undergoing pancreatoduodenectomy at Kaunas University of Medicine Hospital between 2002 and 2004 were collected prospectively. We evaluated etiology and the impact of bile infection on development of post-operative complications. Patients were divided into groups according to results of intraoperative bile culture.; Results: In 31 patients (48.4%) intraoperative bile cultures were negative, while in remaining 33 patients (51.6%) infected bile was documented. Both patient groups were homogenous according to demographic data, preoperative and intraoperative variables. Pancreaticoduodenectomy was performed in 21 patients after preoperative biliary drainage (endoscopic stenting, bilidigestive anastomosis or percutaneous bile drainage), others (n=43) had primary operation. Infected bile was found more often in patients who underwent biliary drainage (p |
| Entry Date(s): | Date Created: 20050611 Date Completed: 20060221 Latest Revision: 20191210 |
| Update Code: | 20260130 |
| PMID: | 15947522 |
| Database: | MEDLINE |
Comparative Study; Evaluation Study; Journal Article