| Title: |
Incidence, clinical features and perinatal outcome in anomalous fetuses with late-onset growth restriction: cohort study. |
| Authors: |
Dall'Asta, A.; Stampalija, T.; Mecacci, F.; Ramirez Zegarra, R.; Sorrentino, S.; Minopoli, M.; Ottaviani, C.; Fantasia, I.; Barbieri, M.; Lisi, F.; Simeone, S.; Castellani, R.; Fichera, A.; Rizzo, G.; Prefumo, F.; Frusca, T.; Ghi, T. |
| Source: |
Ultrasound in Obstetrics & Gynecology; Nov2022, Vol. 60 Issue 5, p632-639, 8p |
| Subject Terms: |
EVALUATION research; SMALL for gestational age; FETAL growth retardation; FETAL ultrasonic imaging; ANEUPLOIDY; LONGITUDINAL method; GESTATIONAL age; RESEARCH; RESEARCH methodology; APGAR score; COMPARATIVE studies; DISEASE incidence |
| Abstract: |
Objective: To describe the incidence, clinical features and perinatal outcome of late-onset fetal growth restriction (FGR) associated with genetic syndrome or aneuploidy, structural malformation or congenital infection.Methods: This was a retrospective multicenter cohort study of patients who attended one of four tertiary maternity hospitals in Italy. We included consecutive singleton pregnancies between 32 + 0 and 36 + 6 weeks' gestation with either fetal abdominal circumference (AC) or estimated fetal weight 50 percentiles from the measurement at an ultrasound scan performed between 18 and 32 weeks. The study group consisted of pregnancies with late-onset FGR and a genetic syndrome or aneuploidy, structural malformation or congenital infection (anomalous late-onset FGR). The presence of congenital anomalies was ascertained postnatally in neonates with abnormal findings on antenatal investigation or detected after birth. The control group consisted of pregnancies with structurally and genetically normal fetuses with late-onset FGR. Composite adverse perinatal outcome was defined as the presence of at least one of stillbirth, 5-min Apgar score |
| : |
Copyright of Ultrasound in Obstetrics & Gynecology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Complementary Index |