[Expression of virus antigens in the cells infected by endotheliotropic or fibroblastotropic human cytomegalovirus strains].
| Title: | [Expression of virus antigens in the cells infected by endotheliotropic or fibroblastotropic human cytomegalovirus strains]. |
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| Authors: | Riaskina SS; Boiarkin AV; Bystrevskaia VB |
| Source: | Voprosy virusologii [Vopr Virusol] 2006 Jan-Feb; Vol. 51 (1), pp. 15-9. |
| Publication Type: | English Abstract; Journal Article |
| Language: | Russian |
| Journal Info: | Publisher: FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora Country of Publication: Russia (Federation) NLM ID: 0417337 Publication Model: Print Cited Medium: Print ISSN: 0507-4088 (Print) Linking ISSN: 05074088 NLM ISO Abbreviation: Vopr Virusol Subsets: MEDLINE |
| Imprint Name(s): | Publication: Moskva : FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora; Original Publication: Moskva : Ministerstvo zdravookhranenii︠a︡ SSSR |
| MeSH Terms: | Antigens, Viral/*metabolism ; Cytomegalovirus/*immunology ; Phosphoproteins/*metabolism ; Viral Matrix Proteins/*metabolism; Endothelial Cells/cytology ; Endothelial Cells/metabolism ; Fibroblasts/cytology ; Fibroblasts/metabolism ; Cell Count ; Cells, Cultured ; Humans ; Serial Passage ; Species Specificity ; Time Factors |
| Abstract: | The time course of changes in the expression of viral antigens was studied in the endotheliocytes and fibroblasts infected by the endothelial strain VHL/E or the fibroblastotropic strain AD169. In the VHL/E-infected cell cultures, the number of the cells containing viral matrix protein pp65 was found to be in the range of 20% to 98% while that of the cells containing the major extra-early viral antigen p72 was not more than 10%. In AD169-infected cultures, about the same quantities of cells were stained with antibodies to p72 and pp65. There is new evidence for differences in the molecular bases of function in the endotheliotropic and fibroblastotropic types of human cytomegalovirus. |
| Substance Nomenclature: | 0 (Antigens, Viral); 0 (Phosphoproteins); 0 (Viral Matrix Proteins); 0 (cytomegalovirus matrix protein 65kDa) |
| Entry Date(s): | Date Created: 20060307 Date Completed: 20060317 Latest Revision: 20161109 |
| Update Code: | 20260130 |
| PMID: | 16515036 |
| Database: | MEDLINE |
English Abstract; Journal Article