Side effects due to primary antituberculosis drugs during the initial phase of therapy in 1149 hospitalized patients for tuberculosis.
| Title: | Side effects due to primary antituberculosis drugs during the initial phase of therapy in 1149 hospitalized patients for tuberculosis. |
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| Authors: | Gülbay BE; Department of Chest Diseases, Ankara University Faculty of Medicine, Ankara, Turkey. banu.gulbay@gmail.com; Gürkan OU; Yildiz OA; Onen ZP; Erkekol FO; Baççioğlu A; Acican T |
| Source: | Respiratory medicine [Respir Med] 2006 Oct; Vol. 100 (10), pp. 1834-42. Date of Electronic Publication: 2006 Mar 06. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Elsevier Country of Publication: England NLM ID: 8908438 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0954-6111 (Print) Linking ISSN: 09546111 NLM ISO Abbreviation: Respir Med Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2003- : Oxford : Elsevier; Original Publication: London : Baillière Tindall, in association with the British Thoracic Society, [c1989- |
| MeSH Terms: | Antitubercular Agents/*adverse effects ; Tuberculosis, Pulmonary/*drug therapy; Hyperuricemia/chemically induced ; Mental Disorders/chemically induced ; Otorhinolaryngologic Diseases/chemically induced ; Adolescent ; Adult ; Aged ; Chemical and Drug Induced Liver Injury ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Retrospective Studies |
| Abstract: | Objective: Side effects of the most commonly used primary antituberculosis (anti-TB) drugs may be mild as well as fatal. The aim of this study was to evaluate the side effects of and the risk factors for developing side effects against anti-TB drugs.; Patients and Methods: Records of 1149 patients with established tuberculosis who initially received anti-TB therapy were evaluated retrospectively. The major side effects, which resulted in a definitive termination from 1 or more drugs related to anti-TB therapy, and the risk factors associated with these side effects, were analyzed.; Results: Ninety-five patients (8.3%), constituting 104 cases in total, experienced side effects. Although the frequency of drug reactions were increased from 0.6% at ages |
| Substance Nomenclature: | 0 (Antitubercular Agents) |
| Entry Date(s): | Date Created: 20060307 Date Completed: 20070927 Latest Revision: 20220316 |
| Update Code: | 20260130 |
| DOI: | 10.1016/j.rmed.2006.01.014 |
| PMID: | 16517138 |
| Database: | MEDLINE |
Journal Article