| Title: |
Living with chemotherapy-induced peripheral neuropathy: a nested qualitative study. |
| Authors: |
Mackereth, Peter; Stringer, Jacqui |
| Source: |
British Journal of Nursing; 11/9/2023, Vol. 32 Issue 20, p978-986, 9p |
| Subject Terms: |
Peripheral neuropathy; Cancer chemotherapy; Acupuncture; Activities of daily living; Randomized controlled trials; Qualitative research; Surveys; Quality of life; Symptoms; Questionnaires; Statistical sampling; Thematic analysis; Psychological distress; Motor ability |
| Abstract: |
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side-effect for patients undergoing a variety of chemotherapy regimens. These effects can have a detrimental impact on patients' quality of life and ability to perform everyday tasks. Objective: This study aimed to explore the experience of living with CIPN prior to and while participating in a randomised study of acupuncture versus a control wait group. Design: The study was nested within a randomised trial (n=120) with participants randomised to acupuncture or to control (wait list for acupuncture). Method: Participants (n=23) volunteered to be interviewed either by telephone (n=20) or face to face (n=3). The audiotapes produced were transcribed verbatim and analysed using a thematic approach. Results: Four themes developed; these included daily life with CIPN, signs and symptoms, interacting with others and management of CIPN. Patients reported compromised dexterity and ability to safely carry out activities. They were often reliant on help and sought out information from others living with the condition. There were also concerns about the lack of effectiveness and the side-effects of medication prescribed. Conclusion: Participants were self-selecting volunteers across different cancer groups, but the information gathered could influence future study designs and increase understanding of the impact of CIPN on patients' lives. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |