| Title: |
Generation of induced pluripotent stem cell lines IRMBi003-A and IRMBi003-B from a healthy donor to model Alzheimer's disease. |
| Authors: |
Clua Provost, C.1 (AUTHOR); Auboyer, L.1,2 (AUTHOR); Rovelet-Lecrux, A.3 (AUTHOR); Monzo, C.1 (AUTHOR); Schob, E.1 (AUTHOR); Andreux, F.1 (AUTHOR); Quittet, C.1 (AUTHOR); Lehmann, S.1 (AUTHOR); Wallon, D.4 (AUTHOR); Crozet, C.1 (AUTHOR) carole.crozet@inserm.fr |
| Source: |
Stem Cell Research. Dec2023, Vol. 73, pN.PAG-N.PAG. 1p. |
| Abstract: |
Induced Pluripotent Stem Cell (iPSC) lines derived from healthy individuals are helpful and essential tools for disease modelling. Here, we described the reprogramming of skin fibroblasts obtained from a healthy 59-year-old individual without Alzheimer's disease. The generated iPSC lines have a normal karyotype, expressed pluripotency markers, and demonstrated the ability to differentiate into the three germ layers. The iPSC lines will be used as controls to study Alzheimer's disease mechanisms. [ABSTRACT FROM AUTHOR] |
| Database: |
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