| Title: |
A petavoxel fragment of human cerebral cortex reconstructed at nanoscale resolution. |
| Authors: |
Shapson-Coe, Alexander; Januszewski, Michał; Berger, Daniel R.; Pope, Art; Yuelong Wu; Blakely, Tim; Schalek, Richard L.; Li, Peter H.; Shuohong Wang; Maitin-Shepard, Jeremy; Karlupia, Neha; Dorkenwald, Sven; Sjostedt, Evelina; Leavitt, Laramie; Lee, Dongil; Troidl, Jakob; Collman, Forrest; Bailey, Luke; Fitzmaurice, Angerica; Kar, Rohin |
| Source: |
Science (pre-March 2025); 5/10/2024, Vol. 384 Issue 6696, p635-635, 1p, 1 Diagram |
| Subject Terms: |
Neural circuitry; Temporal lobe; Human beings; Neuroglia |
| Abstract: |
The article presents a groundbreaking study where a petavoxel fragment of human cerebral cortex was reconstructed at nanoscale resolution, revealing intricate details of neural circuits and synaptic connections. Topics discussed include the methodology of obtaining high-quality human brain tissue, the generation of a petascale dataset through high-throughput serial section electron microscopy, and the identification of previously unrecognized neuronal classes and multisynaptic connections. |
| Database: |
Complementary Index |