| Title: |
Change in Bone Mass after Gluten free Diet in Celiac disease Patients with Gastrointestinal and Non-Gastrointestinal Presentations: An Interventional Study. |
| Authors: |
Lata, Kusum; Verma, Anjali; Khanna, Alok; Singh, Raj; Sachdeva, Ashuma; Verma, Surender |
| Source: |
Indian Journal of Public Health Research & Development; Jul-Sep2024, Vol. 15 Issue 3, p53-57, 5p |
| Subject Terms: |
GLUTEN-free diet; CELIAC disease; CLINICAL trials; DIET in disease; TYPE 1 diabetes; GASTROINTESTINAL diseases |
| Abstract: |
Background and aim: Celiac disease (CD) is an autoimmune enteropathy and gluten free diet (GFD) is the only treatment available till now. Although previous studies had shown that patients with non-gastrointestinal symptoms have osteopenia but there is scanty literature on the effect of GFD on Bone Mass Density (BMD) improvement in celiac disease patients with or without gastrointestinal symptoms in childhood. Methods: A prospective interventional study was conducted in a tertiary care institute in which newly diagnosed children 1 to 14 years of age presented to Pediatrics OPD or admitted in ward with symptoms suggestive of CD and IgA tissue transglutaminase level 10 folds of normal level were taken as cases. Children with other associated diseases like Type 1 Diabetes Mellitus, Hypothyroidism and who were non-compliant to GFD diet were excluded. Those children were later grouped into as children with gastrointestinal and children with non-gastrointestinal symptoms. DEXA scan was done in both the groups at presentation and after 6 months of gluten free diet to determine bone mass density. The results were later compiled and analysed. P value of |
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| Database: |
Complementary Index |