| Title: |
Diagnostic Value of C-Reactive Protein and Interleukin-6 in Prevention of Negative Appendectomy. |
| Authors: |
Layegh, H.; Nezhad, T. Teimour; SeyedSadeghi, M. S. |
| Source: |
Journal of Babol University of Medical Sciences; 2024, Vol. 26 Issue 1, p1-9, 9p |
| Subject Terms: |
UNNECESSARY surgery; ABDOMINAL surgery; C-reactive protein; INTERLEUKIN-6; SURGICAL diagnosis |
| Abstract: |
Background and Objective: Acute appendicitis is one of the common reasons for abdominal surgery in any age group, and most cases are rarely diagnosed, which causes unnecessary surgery (negative appendectomy). The aim of this study is to determine the diagnostic value of C-reactive protein (CRP) and interleukin-6 (IL-6) in the prevention of negative appendectomy. Methods: This cross-sectional study was conducted on 208 patients with acute abdominal surgery and primary diagnosis of acute appendicitis at Fatemi Hospital in Ardabil in a period of 6 months. Creactive protein (CRP) and interleukin-6 (IL-6) levels were measured before surgery in all patients. Patients were divided into positive and negative groups based on pathology results. Then the laboratory results were compared with histopathological findings after surgery. Findings: The level of IL-6 in the positive group was 107.25±3.54 and in the negative group was 75.50±2.41, and the difference was statistically significant (p=0.032). The mean CRP was 35.5±12.1 in the positive group and 11.1±5.3 in the negative group (p |
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| Database: |
Complementary Index |