| Title: |
Is the size of the liver hemangioma affected by the age and gender of the patients? |
| Authors: |
Nikolaev, Evgeni; M., Valcheva; V., Terzi; D., Kostov; I., Mircheva |
| Source: |
Surgical Chronicles; Jan-Mar2025, Vol. 30 Issue 1, p20-25, 6p |
| Subject Terms: |
Age; Gender; Cavernous hemangioma; Tumor growth; Disease prevalence; Hemangiomas; Surgery |
| Abstract: |
Introduction: From a pathogenetic point of view, the most common theory for the formation of liver hemangiomas is a severe disturbance in the embryogenesis of the vascular system of the liver. It has been suggested that treatment with estrogens and steroids, as well as pregnancy, can lead to an increase in the size of an already existing hemangioma, but not to its appearance. Aim: To compare the prevalence and growth rate of hemangioma among different age groups and sexes. Materials and methods: The study included 101 patients with cavernous hemangioma who underwent radical surgery in the Department of Surgery of the Military Medical Academy for the period 2010-2023. Approximately half of the patients were followed prospectively (n = 52), and the rest (n = 49) retrospectively. Gender: 37% male (n = 37), 63% female (n = 64), mean age 54. Results: Men are older than women (p = 0.001), with the largest number of patients in the 55-64 age group. Tumors larger than 10 cm occur in every age group, with the highest incidence in the 35-44 age range, while those larger than 20 cm occur in the 35-65 age range. In both sexes, the largest size of tumors is in the age range of 45-54 years. Discussion. No statistically significant difference was found in the size of hemangiomas in the different age groups in men and women, although the size of the hemangioma was larger in women - 39 of the hemangiomas over 10 cm were in women, while in men 16 of the tumors were over 10 cm. In patients >50 years of age, hepatic hemangiomas may grow slowly or stop growing, and surgical treatment may be unnecessary if no complications are caused by the tumor. However, for younger patients, growth potential may be considered in decision making. Conclusion: Although the results of our study were not statistically significant, age and gender seem to be important factors influencing tumor growth. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |