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Submucosal hematoma presenting as small bowel obturator obstruction in a patient on low-molecular-weight heparin.

Title: Submucosal hematoma presenting as small bowel obturator obstruction in a patient on low-molecular-weight heparin.
Authors: Kalu ON; Department of Pediatric Surgery, Long Island College Hospital, State University of New York-Downstate, Brooklyn, NY 11226, USA. ogorikalu@yahoo.com; Al-Khoury G; Reck CA; Velcek F
Source: Journal of pediatric surgery [J Pediatr Surg] 2008 Aug; Vol. 43 (8), pp. 1569-71.
Publication Type: Case Reports; Journal Article
Language: English
Journal Info: Publisher: Saunders Country of Publication: United States NLM ID: 0052631 Publication Model: Print Cited Medium: Internet ISSN: 1531-5037 (Electronic) Linking ISSN: 00223468 NLM ISO Abbreviation: J Pediatr Surg Subsets: MEDLINE
Imprint Name(s): Publication: Philadelphia, PA : Saunders; Original Publication: New York.
MeSH Terms: Intestine, Small*; Enoxaparin/*adverse effects ; Gastrointestinal Hemorrhage/*chemically induced ; Hematoma/*chemically induced ; Heparin, Low-Molecular-Weight/*adverse effects ; Intestinal Obstruction/*etiology ; Intestinal Obstruction/*surgery; Enoxaparin/therapeutic use ; Gastrointestinal Hemorrhage/complications ; Gastrointestinal Hemorrhage/surgery ; Hematoma/complications ; Hematoma/surgery ; Heparin, Low-Molecular-Weight/therapeutic use ; Intestinal Obstruction/diagnostic imaging ; Laparotomy/methods ; Venous Thrombosis/diagnosis ; Venous Thrombosis/drug therapy ; Anastomosis, Surgical ; Child, Preschool ; Female ; Follow-Up Studies ; Humans ; Risk Assessment ; Severity of Illness Index ; Tomography, X-Ray Computed ; Treatment Outcome
Abstract: Recent studies have shown the efficacy of low-molecular-weight heparin (LMWH) in the treatment of venous thromboembolic disease in children. Compared to unfractionated heparin and coumadin, LMWH has more predictable pharmacokinetics and a reported lower incidence of osteoporosis and heparin-induced thrombocytopenia in children. The overall incidence of severe hemorrhage on LMWH in children is low. To date, there is a single report of a small bowel obstruction in a child secondary to a hematoma while on LMWH. We report the second case of a child, on enoxaparin (Lovenox) therapy, who underwent bowel resection secondary to a completely obstructing small bowel wall hematoma.
Substance Nomenclature: 0 (Enoxaparin); 0 (Heparin, Low-Molecular-Weight)
Entry Date(s): Date Created: 20080805 Date Completed: 20081126 Latest Revision: 20161124
Update Code: 20260130
DOI: 10.1016/j.jpedsurg.2008.03.067
PMID: 18675658
Database: MEDLINE

Case Reports; Journal Article