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Predictors of Alzheimer's Disease Treatment Optimism Among a Nationally Representative Sample of Older Adults.

Title: Predictors of Alzheimer's Disease Treatment Optimism Among a Nationally Representative Sample of Older Adults.
Authors: McCain, Sarah1 (AUTHOR) smmccain@umich.edu; Reader, Jonathan M2 (AUTHOR); Roberts, J. Scott1 (AUTHOR)
Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association. Dec2025 Supplement, Vol. 21 Issue S4, p1-4. 4p.
Abstract: Background: The health psychology literature suggests that treatment optimism (i.e., the belief that disease‐specific treatments' efficacy and availability will significantly improve over time) may predict help‐seeking and influence medical decisions (e.g., disease screening and early detection). However, little is known about treatment optimism regarding Alzheimer's disease (AD). This secondary data analysis describes AD treatment optimism and its predictors among a nationally representative sample of older adults in the US. Method: The National Poll on Healthy Aging (NPHA), a recurring, nationally representative survey of adults aged 50 and older, conducted a cross‐sectional internet and telephone survey in 2023 using NORC's AmeriSpeak Panel®. Survey measures included self‐reported demographic/health characteristics (e.g., family history of AD) and dementia‐related perceptions (e.g., concern about developing AD, subjective memory rating). The main outcome measure assessed AD treatment optimism by asking respondents to rate their agreement (1=Strongly Disagree to 5=Strongly Disagree) with the statement: "AD will one day become a manageable chronic condition like diabetes or heart disease." Logistic regression modeling identified predictors of treatment optimism, utilizing a significance value of p
Database: Supplemental Index