| Title: |
The Incubation Periods of Mpox Virus Clade Ib. |
| Authors: |
Perez-Saez, Javier; Bugeme, Patrick Musole; O'Driscoll, Megan; Bugale, Patrick Kazuba; Mukika, Trust Faraja; Bugwaja, Levi; Shangula, Salomon Mashupe; Bengehya, Justin; Ngai, Stephanie; Carrion Martin, Antonio Isidro; Jackson, Jules; Mulopo-Mukanya, Noella; Knee, Jackie; Eckerle, Isabella; Lee, Elizabeth C.; Mukadi-Bamuleka, Daniel; Lessler, Justin; Azman, Andrew S.; Malembaka, Espoir Bwenge |
| Source: |
Annals of Internal Medicine; Feb2026, Vol. 179 Issue 2, p207-215, 10p |
| Subject Terms: |
Poxviruses; Bayesian analysis; Preventive medicine |
| Geographic Terms: |
Congo (Democratic Republic) |
| Company/Entity: |
World Health Organization |
| Abstract: |
Mpox virus clade Ib, first detected in the Democratic Republic of the Congo in September 2023, spread internationally within months, prompting a World Health Organization emergency declaration. This study estimates the incubation periods of mpox clade Ib examining evidence for differences by route of exposure and demographic factors. Background: Mpox virus (MPXV) clade Ib, first detected in the Democratic Republic of the Congo (DRC) in September 2023, spread internationally within months, prompting an emergency declaration from the World Health Organization. Data on its incubation period, which both shapes outbreak dynamics and informs epidemic response strategies, remain limited. Objective: To estimate the incubation periods of mpox clade Ib, examining evidence for differences by route of exposure and demographic factors. Design: Bayesian analysis of clinical surveillance data collected between June and October 2024. Setting: South Kivu, DRC, the epicenter of the current mpox clade Ib global outbreak. Participants: Clinically attended persons with confirmed mpox clade Ib infection. Measurements: Demographic characteristics, exposure history, symptom onset, and transmission route. Results: Among 37 polymerase chain reaction–confirmed cases with high viral load (cycle threshold values |
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| Database: |
Complementary Index |