| Title: |
Sex differences in the prevalence and prognosis of tricuspid regurgitation among patients with heart failure. |
| Authors: |
Mattig, Isabel; Dorta, Elena Romero; Frumkin, David; Kretzschmar, Hannes; Sommer, Alexander; Redel, Alva Morgane; Buchstaller, Johannes; Gómez, Osvaldo Jesús Sánchez; Pieske-Kraigher, Elisabeth; Stegherr, Regina; Stangl, Karl; Hindricks, Gerhard; Dreger, Henryk |
| Source: |
Heart; Mar2026, Vol. 112 Issue 5, p285-292, 8p |
| Subject Terms: |
HEART failure patients; DISEASE prevalence; MITRAL valve insufficiency; TRICUSPID valve diseases; ECHOCARDIOGRAPHY |
| Abstract: |
Background Tricuspid regurgitation (TR) is a common finding in heart failure (HF) and is associated with adverse outcomes. Data about sex differences in TR prevalence, aetiology and prognosis among patients with HF and their subgroups are still scarce. Methods Patients with HF with a recent transthoracic echocardiography were enrolled in our registry (NCT04570098). Based on a left ventricular ejection fraction (LVEF) cut-off of 50%, patients were divided into those with reduced (rEF) and preserved ejection fraction (pEF). Follow-ups were conducted after 3, 6 and 12 months. Analysis was performed in the overall cohort and after matching for age and comorbidities. Results Between 2020 and 2022, 1012 patients with HF were prospectively enrolled, including 38% women. pEF was more prevalent among females (60%), whereas rEF was more common among males (60%) (p |
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| Database: |
Complementary Index |