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Primary Fontan operation in adults: Challenges and early outcomes in adults at a tertiary cardiac centre in India.

Title: Primary Fontan operation in adults: Challenges and early outcomes in adults at a tertiary cardiac centre in India.
Authors: Mishra, Anand Kumar; Edem, Sanketh; Reddy, Lasya; Rohit, Manojkumar K; Kheni, Akshay; Jaswal, Vivek; Sangdup, Tsering; Singh, Harkant
Source: Asian Cardiovascular & Thoracic Annals; Mar2026, Vol. 34 Issue 3, p235-241, 7p
Abstract: Background: The Fontan operation is the definitive palliation for single-ventricle physiology. In low- and middle-income countries, delayed diagnosis and limited paediatric cardiac services often result in adults presenting for primary Fontan rather than staged completion. Methods: Adults (≥18 years) undergoing extracardiac or lateral-tunnel Fontan between January 2021 and June 2025 were retrospectively reviewed. Variables included demographics, conduit and fenestration, cardiopulmonary bypass and cross-clamp times, re-exploration, extubation time, intensive care unit (ICU) stay, pulmonary-artery pressure, atrioventricular valve regurgitation, pleural effusion >14 days, arrhythmia and survival. Results: Twenty-four adults (median age 20.5 years (interquartile range 19–22); 17 males (71%)) underwent primary Fontan: 18 (75%) extracardiac and 6 (25%) lateral tunnel. Fenestration was created in 14 (58%). Mean pulmonary-artery pressure increased from 12.6 ± 3.2 to 13.7 ± 3.5 mmHg (p =.12). Systemic oxygen saturation improved significantly from 79 ± 4% to 92.8 ± 3.1% (p
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Database: Complementary Index