| Title: |
EMERGING IMAGING BIOMARKERS IN ABDOMINAL TUBERCULOSIS: FROM MORPHOLOGY TO FUNCTIONAL IMAGING. |
| Authors: |
Gupta, Anoushka; Shukla, Ashish Kumar; Modi, Bhoomi; Dhingra, Manvi; Yadav, Jyoti; Singh, Ranjeet |
| Source: |
International Journal of Medicine & Public Health; Jan-Mar2026, Vol. 16 Issue 1, p392-398, 7p |
| Subject Terms: |
TUBERCULOSIS; DIAGNOSTIC imaging; MAGNETIC resonance imaging; DIFFUSION magnetic resonance imaging; POSITRON emission tomography computed tomography; COMPUTED tomography; COMPUTER-assisted image analysis (Medicine) |
| Abstract: |
Background: Abdominal tuberculosis (TB) poses significant diagnostic challenges due to its nonspecific clinical manifestations and overlapping imaging features with other intra-abdominal pathologies. Emerging imaging biomarkers have shown potential for early, non-invasive and more accurate detection. Materials and Methods: A systematic review of imaging literature published between January 2015 and May 2025 was conducted, focusing on both morphological and functional imaging modalities in the evaluation of abdominal TB. Results: CT and MRI remain the cornerstone imaging modalities for morphological assessment, identifying features such as bowel wall thickening, necrotic lymphadenopathy, and ascites. However, advanced techniques such as diffusion-weighted imaging (DWI), apparent diffusion coefficient (ADC) mapping, PET-CT, and radiomics are increasingly recognized for their ability to offer functional insights. These biomarkers enhance diagnostic precision, particularly in distinguishing TB from malignancies and other mimicking conditions. Conclusion: Imaging biomarkers—particularly functional and AI-enhanced tools—are redefining the diagnostic paradigm of abdominal TB. Their successful translation into routine clinical practice will require standardized imaging protocols, unified biomarker thresholds, and validation through large-scale multicentric studies. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |