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Knowledge preservation in the era of big science and AI: strategies for sustainable scientific research.

Title: Knowledge preservation in the era of big science and AI: strategies for sustainable scientific research.
Authors: Rainford, Penn F.; Occhipinti, Annalisa; Wang, Bo; Stepney, Susan; Angione, Claudio; Verma, Suraj; Marucci, Lucia; Sharma, Kieren; Harris, Sarah A.; Füchslin, Rudolf M.; Klipp, Edda; Grierson, Claire S.; Weyland, Mathias S.; Mogre, Aalap; Fellermann, Harold; Doan, Le Minh Thao; Gherman, Ioana M.; Pyne, Alice L. B.; Rudge, Timothy J.; Berrelleza, Victor M. V.
Source: Nature Communications; 5/5/2026, Vol. 17 Issue 1, p1-12, 12p
Subject Terms: DOCUMENTATION standards; DIGITAL preservation; ARTIFICIAL intelligence; OPEN scholarship; UNIVERSITY research; DIGITAL technology
Abstract: Science is losing knowledge it cannot afford to lose. Negative results go unpublished, hard-won expertise walks out the door with departing researchers, and preservation efforts remain fragmented. The consequences are wasted resources, duplicated effort, and missed discoveries. In this perspective, we argue that the research community can act now by embracing alternative dissemination channels, improving documentation best practices, and building sustainable digital infrastructure. We envision moderated platforms for sharing null results and practical know-how, community-driven standards, and AI-powered tools that lower barriers to implementation. With coordinated effort, science can become more open, efficient, and resilient for future generations. Science routinely discards valuable knowledge, from unpublished negative results to the tacit expertise lost when researchers move on. Here, the authors propose a roadmap for preserving this hidden knowledge through community-driven platforms, open standards, and AI-assisted documentation. [ABSTRACT FROM AUTHOR]
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Database: Complementary Index