| Title: |
Prevalence of qnrA, qnrB, and qnrS Genes in Klebsiella pneumoniae Isolates From Patients in Hospitals in Sabzevar, Iran: A Cross-sectional From February 2022 to October 2023. |
| Authors: |
Kheirabadi, Faezeh; Rostazadeh, Maryam; Javaheri, Ehsan; Navidifar, Tahereh; Shahrestanaki, Mohammad Keyvanloo; Mojahedifar, Mahta; Khoshnood, Saeed; Heidary, Mohsen; Faraji, Reza |
| Source: |
Archives of Razi Institute; Mar/Apr2026, Vol. 81 Issue 2, p375-384, 10p |
| Abstract: |
Introduction: Klebsiella pneumoniae has emerged as a significant opportunistic pathogen responsible for nosocomial infections, including hospital-acquired pneumonia (HAP) and various intra-abdominal infections. The aim of this study was to investigate the prevalence of qnrA, qnrB, and qnrS genes in K. pneumoniae isolates from patients in hospitals in Sabzevar, Iran. Materials & Methods: Of 100 specimens of urine, respiratory secretions, blood, tracheal lavage, pleural fluid and trachea were collected from patients referred to hospitals in Sabzevar, northeastern Iran. Identification of bacteria was performed by gram stain, culture characteristics and biochemical methods. Bacterial susceptibility to quinolone antibiotics using the Kirby-Bauer disk diffusion method according to Clinical Laboratory Standards Institute (CLSI) guidelines (2023). The extracted DNA was subjected to polymerase chain reaction (PCR) assay targeting three genes of qnrA, qnrB and qnrS using specific primers. The data were analyzed using the chi-squared test and the Fisher's exact test with the IBM SPSS Statistics version 26 software. P |
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| Database: |
Complementary Index |