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International consensus report on the investigation and management of primary immune thrombocytopenia.

Title: International consensus report on the investigation and management of primary immune thrombocytopenia.
Authors: Provan D; Department of Haematology, Barts and The London School of Medicine and Dentistry, London, United Kingdom. a.b.provan@qmul.ac.uk; Stasi R; Newland AC; Blanchette VS; Bolton-Maggs P; Bussel JB; Chong BH; Cines DB; Gernsheimer TB; Godeau B; Grainger J; Greer I; Hunt BJ; Imbach PA; Lyons G; McMillan R; Rodeghiero F; Sanz MA; Tarantino M; Watson S; Young J; Kuter DJ
Source: Blood [Blood] 2010 Jan 14; Vol. 115 (2), pp. 168-86. Date of Electronic Publication: 2009 Oct 21.
Publication Type: Consensus Statement; Journal Article; Practice Guideline; Research Support, Non-U.S. Gov't; Review
Language: English
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Imprint Name(s): Publication: 2021- : [New York] : Elsevier; Original Publication: New York, Grune & Stratton [etc.]
MeSH Terms: Pregnancy Complications, Hematologic/*diagnosis ; Pregnancy Complications, Hematologic/*drug therapy ; Purpura, Thrombocytopenic, Idiopathic/*diagnosis ; Purpura, Thrombocytopenic, Idiopathic/*drug therapy; Pregnancy Complications, Hematologic/physiopathology ; Purpura, Thrombocytopenic, Idiopathic/physiopathology ; Adult ; Child ; Child, Preschool ; Consensus ; Female ; Humans ; Male ; Pregnancy
Abstract: Previously published guidelines for the diagnosis and management of primary immune thrombocytopenia (ITP) require updating largely due to the introduction of new classes of therapeutic agents, and a greater understanding of the disease pathophysiology. However, treatment-related decisions still remain principally dependent on clinical expertise or patient preference rather than high-quality clinical trial evidence. This consensus document aims to report on new data and provide consensus-based recommendations relating to diagnosis and treatment of ITP in adults, in children, and during pregnancy. The inclusion of summary tables within this document, supported by information tables in the online appendices, is intended to aid in clinical decision making.
Number of References: 207
Entry Date(s): Date Created: 20091023 Date Completed: 20100128 Latest Revision: 20260128
Update Code: 20260130
DOI: 10.1182/blood-2009-06-225565
PMID: 19846889
Database: MEDLINE

Consensus Statement; Journal Article; Practice Guideline; Research Support, Non-U.S. Gov't; Review