[Clinical features of coronary heart disease with concomitant diabetes mellitus at high latitudes].
| Title: | [Clinical features of coronary heart disease with concomitant diabetes mellitus at high latitudes]. |
|---|---|
| Authors: | Kuznetsov VA; Bessonova MI; Bessonov IS; Zyrianov IP; Kolunin GV; Semukhin MV; Krinochkin DV; Gorbatenko EA; Bektasheva ASh |
| Source: | Klinicheskaia meditsina [Klin Med (Mosk)] 2009; Vol. 87 (9), pp. 29-32. |
| Publication Type: | Comparative Study; English Abstract; Journal Article |
| Language: | Russian |
| Journal Info: | Publisher: Med. informat︠s︡ionnoe agentstvo Country of Publication: Russia (Federation) NLM ID: 2985204R Publication Model: Print Cited Medium: Print ISSN: 0023-2149 (Print) Linking ISSN: 00232149 NLM ISO Abbreviation: Klin Med (Mosk) Subsets: MEDLINE |
| Imprint Name(s): | Publication: Moskva : Med. informat︠s︡ionnoe agentstvo; Original Publication: Moskva. |
| MeSH Terms: | Altitude*; Coronary Artery Disease/*complications ; Diabetes Mellitus, Type 2/*complications ; Environmental Exposure/*adverse effects; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/epidemiology ; Diabetes Mellitus, Type 2/epidemiology ; Siberia/epidemiology ; Adult ; Aged ; Coronary Angiography ; Electrocardiography ; Exercise Test ; Female ; Humans ; Male ; Middle Aged ; Morbidity |
| Abstract: | Joint effect of diabetes mellitus (DM) and extreme natural conditions of the Far North on the clinical course of coronary heart disease (CHD) remains poorly known. Specific features of DM2 concomitant with CHD were studied in 243 of the 8573 subjects living in Far North areas of the Tyumen region and examined by coronarography (mean age 53.4 +/- 0.4 years). The control group comprised 139 patients (56.9 +/- 0.58 years) with CHD and DM2 living in the south of Tyumen region. Clinical and ECG observations were supplemented by measurement of total cholesterol and selective coronarography. Patients of the study group were younger (p < 0.001), more frequently consumed tobacco (p < 0.001) and alcohol (p = 0.001) and had obesity (p = 0.008). Most patients in both groups had a history of myocardial infarction, suffered functional class II or higher angina and circulatory insufficiency (according to NYHA), high cholesterolemia, and arterial hypertension further deteriorating effects of CHD and DM2. However, the two groups were not significantly different in terms of these characteristics. It is concluded that combination of CDH and DM2 has unfavourable effect in patients living in the Far North although severity of clinical and functional manifestations of CDH in DM2 patients is not significantly different between residents of northern and southern areas of Tyumen region. |
| Entry Date(s): | Date Created: 20091104 Date Completed: 20091215 Latest Revision: 20091103 |
| Update Code: | 20260130 |
| PMID: | 19882876 |
| Database: | MEDLINE |
Comparative Study; English Abstract; Journal Article