[Erosive reflux-esophagitis and its treatment].
| Title: | [Erosive reflux-esophagitis and its treatment]. |
|---|---|
| Transliterated Title: | Erozivnyĭ refliuks-ézofagit i ego lechenie. |
| Authors: | Geller LI; Bessonova GA; Petrenko VF |
| Source: | Terapevticheskii arkhiv [Ter Arkh] 1991; Vol. 63 (1), pp. 81-4. |
| Publication Type: | English Abstract; Journal Article |
| Language: | Russian |
| Journal Info: | Publisher: ZAO 'Konsilium Medikum Country of Publication: Russia (Federation) NLM ID: 2984818R Publication Model: Print Cited Medium: Print ISSN: 0040-3660 (Print) Linking ISSN: 00403660 NLM ISO Abbreviation: Ter Arkh Subsets: MEDLINE |
| Imprint Name(s): | Publication: : Moskva : ZAO 'Konsilium Medikum'; Original Publication: Moskva : Izdatelʹstvo Medit︠s︡ina |
| MeSH Terms: | Esophagitis, Peptic/*drug therapy; Duodenal Ulcer/complications ; Duodenitis/complications ; Esophagitis, Peptic/etiology ; Gastritis/complications ; Adult ; Humans ; Middle Aged |
| Abstract: | Altogether 78 patients were examined over time. They had erosive reflux esophagitis that complicated the course of duodenal ulcer (in 42 patients, hypersecretion of hydrochloric acid was the leading mechanism of the disease development) and chronic gastroduodenitis (36 persons manifested failure of the inferior sphincter of the esophagus with or without excess acid output). In patients with peptic ulcer exacerbation, the four-week treatment with cimetidine or gastrozepine compared very favourably with almagel and vicalin as regards the treatment efficacy. In chronic gastroduodenitis, the combination of almagel, vicalin and cerucal produced a therapeutic effect that did not yield to the effect of cimetidine or gastrozepine. In 1/5-2/5 of cases, erosive esophagitis was not amenable by the four-week treatment. In 17 out of 18 such patients, the two-week therapy with sucralfat (venter) resulted in the disappearance of esophagitis with multiple erosions. During 1-2 years, erosive reflux esophagitis recurred in 11 out of 34 patients with peptic ulcer and in 2 out of 17 suffering from chronic gastroduodenitis. In all the cases, the disease recurred in those patients who had not received systematic treatment with antisecretory and cytoprotector agents. |
| Entry Date(s): | Date Created: 19910101 Date Completed: 19910801 Latest Revision: 20061115 |
| Update Code: | 20260130 |
| PMID: | 2057905 |
| Database: | MEDLINE |
English Abstract; Journal Article