[Minimization of endogenous intoxication syndrome by individual choice of drugs for therapy of chronic hepatitis].
| Title: | [Minimization of endogenous intoxication syndrome by individual choice of drugs for therapy of chronic hepatitis]. |
|---|---|
| Authors: | Vasil'eva DK; Goriacheva LG; Kotiv MIa; Alekseeva LA; Romantsov MG; Bessonova TV |
| Source: | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] [Antibiot Khimioter] 2011; Vol. 56 (3-4), pp. 46-50. |
| Publication Type: | Journal Article |
| Language: | Russian |
| Journal Info: | Publisher: Izdatelstvo Meditsina Country of Publication: Russia (Federation) NLM ID: 8803688 Publication Model: Print Cited Medium: Print ISSN: 0235-2990 (Print) Linking ISSN: 02352990 NLM ISO Abbreviation: Antibiot Khimioter Subsets: MEDLINE |
| Imprint Name(s): | Publication: Moskva : Izdatelstvo Meditsina; Original Publication: Moskva : Meditsina, c1988- |
| MeSH Terms: | Acridines/*therapeutic use ; Antiviral Agents/*therapeutic use ; Interferon Inducers/*therapeutic use ; Interferon-alpha/*therapeutic use ; Ribavirin/*therapeutic use; Acridines/economics ; Antiviral Agents/economics ; Asymptomatic Infections/therapy ; Biomarkers/analysis ; Cost-Benefit Analysis/economics ; Hepatitis B, Chronic/diagnosis ; Hepatitis B, Chronic/drug therapy ; Hepatitis B, Chronic/economics ; Hepatitis C, Chronic/diagnosis ; Hepatitis C, Chronic/drug therapy ; Hepatitis C, Chronic/economics ; Interferon Inducers/economics ; Interferon-alpha/economics ; Ribavirin/economics ; Adolescent ; Child ; Child, Preschool ; Drug Therapy, Combination ; Humans ; Treatment Outcome |
| Abstract: | The results of clinical and laboratory examination of 107 children suffering from chronic hepatitis B or C were analysed. The biochemical criteria of the endogenous intoxication were investigated. Specific blood tests with antiviral drugs were conducted before the treatment and individual therapy schemes were assigned according to the tests' results. The early and sustained virological response rates during the individual antiviral treatment of the children with chronic hepatitis C proved to be 70.83 and 62.5% respectively. |
| Substance Nomenclature: | 0 (Acridines); 0 (Antiviral Agents); 0 (Biomarkers); 0 (Interferon Inducers); 0 (Interferon-alpha); 49717AWG6K (Ribavirin); X91E9EME19 (10-carboxymethyl-9-acridanone) |
| Entry Date(s): | Date Created: 20110915 Date Completed: 20111118 Latest Revision: 20181109 |
| Update Code: | 20260130 |
| PMID: | 21913409 |
| Database: | MEDLINE |
Journal Article