Evaluating the effect of magnesium and magnesium plus vitamin B6 supplement on the severity of premenstrual syndrome.
| Title: | Evaluating the effect of magnesium and magnesium plus vitamin B6 supplement on the severity of premenstrual syndrome. |
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| Authors: | Fathizadeh N; Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.; Ebrahimi E; Valiani M; Tavakoli N; Yar MH |
| Source: | Iranian journal of nursing and midwifery research [Iran J Nurs Midwifery Res] 2010 Dec; Vol. 15 (Suppl 1), pp. 401-5. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Medknow Publications Country of Publication: India NLM ID: 101558775 Publication Model: Print Cited Medium: Internet ISSN: 2228-5504 (Electronic) Linking ISSN: 17359066 NLM ISO Abbreviation: Iran J Nurs Midwifery Res Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: Mumbai : Medknow Publications |
| Abstract: | Background: Since premenstrual syndrome (PMS) can cause suicide, dissociation of familial relationships, abnormalities in the daily work and inter-personal relationships in the patients, and bring about direct and indirect economic burden for the society, it is important to resolve the problems of the patients. The objective of the current study is to determine the effect of magnesium (Mg), combination of vitamin B6 and Mg, and the placebo on the severity of PMS in the patients affected by the disease referred to the health centers of Isfahan University of Medical Sciences during 2009-2010.; Methods: The participants were randomly assigned to two intervention groups and one control group. The study was carried out for four months in ten selected health centers in Isfahan. To confirm the PMS diagnosis in patients, they were asked to fill out the PMS daily symptom record form for two months and then, when the diagnosis was confirmed, the participants were randomly assigned to one of the three groups of the study (Mg, Mg plus vitamin B6, and placebo). Medical intervention was carried out in two menstrual cycles and the results of pre- and post-test were compared.; Results: After the intervention, the mean score of PMS significantly decreased in all the three groups (p < 0.05). The decrease was the greatest in the Mg plus vitamin B6 group, and was the least in the placebo group.; Conclusions: The findings indicated that Mg plus vitamin B6 and placebo has the greatest and the least effect on the mean score of PMS, respectively. |
| References: | Clin Drug Investig. 2007;27(1):51-8. (PMID: 17177579); J Womens Health. 1998 Nov;7(9):1157-65. (PMID: 9861593); Obstet Gynecol. 1991 Aug;78(2):177-81. (PMID: 2067759); West J Nurs Res. 2009 Mar;31(2):171-86. (PMID: 18829443); Int J Gynaecol Obstet. 2009 May;105(2):158-61. (PMID: 19232611); J Am Coll Nutr. 1991 Oct;10(5):494-9. (PMID: 1955626); J Womens Health Gend Based Med. 2000 Mar;9(2):131-9. (PMID: 10746516) |
| Contributed Indexing: | Keywords: Premenstrual syndrome; magnesium; vitamin B6 |
| Entry Date(s): | Date Created: 20111110 Date Completed: 20111110 Latest Revision: 20211021 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC3208934 |
| PMID: | 22069417 |
| Database: | MEDLINE |
Journal Article