Subclinical thyroid disease.
| Title: | Subclinical thyroid disease. |
|---|---|
| Authors: | Garg A; Department of Endocrinology, Royal Free London NHS Foundation Trust, Pond Street, London NW3 2QG, UK.; Vanderpump MP |
| Source: | British medical bulletin [Br Med Bull] 2013; Vol. 107, pp. 101-16. Date of Electronic Publication: 2013 Aug 06. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0376542 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-8391 (Electronic) Linking ISSN: 00071420 NLM ISO Abbreviation: Br Med Bull Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2001- : London : Oxford University Press; Original Publication: London. |
| MeSH Terms: | Hyperthyroidism/*diagnosis ; Hyperthyroidism/*drug therapy ; Hypothyroidism/*diagnosis ; Hypothyroidism/*drug therapy; Hyperthyroidism/etiology ; Hypothyroidism/etiology ; Pregnancy Complications/diagnosis ; Pregnancy Complications/drug therapy ; Pregnancy Complications/epidemiology ; Thyroid Diseases/diagnosis ; Thyroid Diseases/epidemiology ; Thyroid Gland/physiopathology ; Female ; Humans ; Male ; Pregnancy ; Thyroiditis, Autoimmune |
| Abstract: | Introduction: Subclinical thyroid disease is a common finding on testing of thyroid function and its management remains controversial.; Source of Data: Epidemiological data from large population studies from USA and Europe.; Areas of Agreement: There is an increased risk of progression to overt hypothyroidism or hyperthyroidism. The treatment of mild thyroid failure is of importance in optimizing pregnancy outcome.; Areas of Controversy: Diagnostic criteria differ and there is variation between management guidelines. The difference was found in long-term clinical outcomes between endogenous and exogenous subclinical hyperthyroidism.; Growing Points: Meta-analyses have provided epidemiological data in cardiovascular mortality and morbidity in subclinical thyroid disease. Increased use of echocardiography and bone markers in identifying those who benefit from intervention.; Areas Timely for Developing Research: A randomized controlled trial to identify those subjects identified from screening programmes that benefit from intervention in terms of morbidity and mortality. |
| Contributed Indexing: | Keywords: autoimmune thyroid disease; screening; subclinical hyperthyroidism; subclinical hypothyroidism |
| Entry Date(s): | Date Created: 20130808 Date Completed: 20140303 Latest Revision: 20130904 |
| Update Code: | 20260130 |
| DOI: | 10.1093/bmb/ldt024 |
| PMID: | 23919951 |
| Database: | MEDLINE |
Journal Article