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Assessment of the relationship between aortic stiffness and left ventricular functions with echocardiography in patients with Sjögren's syndrome.

Title: Assessment of the relationship between aortic stiffness and left ventricular functions with echocardiography in patients with Sjögren's syndrome.
Authors: Ciçek OF; Department of Cardiology, Ankara Ataturk Education and Research Hospital, Ankara, Turkey.; Bayram NA; Ayhan H; Erten S; Aslan AN; Sarı C; Ozen MB; Bİlen E; Bastuğ S; Durmaz T; Keleş T; Bozkurt E
Source: International journal of rheumatic diseases [Int J Rheum Dis] 2014 Jul; Vol. 17 (6), pp. 658-63. Date of Electronic Publication: 2013 Dec 14.
Publication Type: Journal Article
Language: English
Journal Info: Publisher: Wiley on behalf of the Asia Pacific League of Associations for Rheumatology Country of Publication: England NLM ID: 101474930 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-185X (Electronic) Linking ISSN: 17561841 NLM ISO Abbreviation: Int J Rheum Dis Subsets: MEDLINE
Imprint Name(s): Original Publication: [Oxford, UK] : Wiley on behalf of the Asia Pacific League of Associations for Rheumatology
MeSH Terms: Echocardiography, Doppler* ; Vascular Stiffness* ; Ventricular Function, Left*; Aortic Diseases/*diagnostic imaging ; Sjogren's Syndrome/*complications ; Ventricular Dysfunction, Left/*diagnostic imaging; Aortic Diseases/etiology ; Aortic Diseases/physiopathology ; Sjogren's Syndrome/physiopathology ; Ventricular Dysfunction, Left/etiology ; Ventricular Dysfunction, Left/physiopathology ; Adult ; Case-Control Studies ; Female ; Humans ; Male ; Middle Aged ; Myocardial Contraction ; Predictive Value of Tests ; Risk Factors ; Stroke Volume
Abstract: Background and Aim: Capable of multi-organ involvement in Sjogren's syndrome (SS), cardiac findings of pulmonary effusion, left ventricular diastolic dysfunction and pulmonary hypertension are seen in patients with SS. Aortic stiffness (AS) reflects the mechanical tension and elasticity of the aorta. In this study, our aim is to determine if there is any differences in AS and left ventricular function between patients diagnosed as SS and healthy control groups.; Methods and Results: We enrolled 50 patients with SS and 47 healthy volunteers with similar demographic characteristics. It was found that isovolumetric relaxation time (IVRT) and deceleration time (DT) were significantly longer and early diastolic wave (E) was significantly lower in patients with SS, but there was no difference in the other parameters. When tissue Doppler echocardiography (TDE) findings were compared between the two groups, it was found that myocardial systolic wave (Sm), myocardial early diastolic wave (Em) and Em/Am ratio were significantly lower, and myocardial isovolumetric relaxation time (IVRTm) and myocardial performance index (MPI) values were significantly higher in patients with SS. A significant positive correlations between aortic strain and Sm (r = 0.35, P 
Contributed Indexing: Keywords: Sjogren's syndrome; aortic stiffness; left ventricular diastolic function; tissue Doppler echocardiography
Entry Date(s): Date Created: 20131217 Date Completed: 20150629 Latest Revision: 20161125
Update Code: 20260130
DOI: 10.1111/1756-185X.12258
PMID: 24330340
Database: MEDLINE

Journal Article