Esophageal atresia and transitional care--step 1: a systematic review and meta-analysis of the literature to define the prevalence of chronic long-term problems.
| Title: | Esophageal atresia and transitional care--step 1: a systematic review and meta-analysis of the literature to define the prevalence of chronic long-term problems. |
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| Authors: | Connor MJ; Department of Pediatric and Neonatal Surgery, St. George's Healthcare NHS Trust, University of London, London, UK.; Springford LR; Department of Pediatric and Neonatal Surgery, St. George's Healthcare NHS Trust, University of London, London, UK.; Kapetanakis VV; Population Health Research Institute, St. George's University of London, London, UK.; Giuliani S; Department of Pediatric and Neonatal Surgery, St. George's Healthcare NHS Trust, University of London, London, UK. Electronic address: stefano.giuliani@nhs.net. |
| Source: | American journal of surgery [Am J Surg] 2015 Apr; Vol. 209 (4), pp. 747-59. Date of Electronic Publication: 2014 Dec 04. |
| Publication Type: | Journal Article; Meta-Analysis; Systematic Review |
| Language: | English |
| Journal Info: | Publisher: Excerpta Medica Country of Publication: United States NLM ID: 0370473 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1883 (Electronic) Linking ISSN: 00029610 NLM ISO Abbreviation: Am J Surg Subsets: MEDLINE |
| Imprint Name(s): | Publication: Belle Mead, NJ : Excerpta Medica; Original Publication: New York. |
| MeSH Terms: | Esophageal Atresia/*surgery; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Chronic Disease ; Humans ; Prevalence ; Time Factors |
| Abstract: | Background: Esophageal atresia (EA) is a rare congenital anomaly with high infantile survival rates. The aim of this study was to outline the prevalence of common long-term problems associated with EA repair in patients older than 10 years of age.; Data Sources: Original papers were identified by systematic searching of MEDLINE and EMBASE databases from January 1993 to July 2014. Fifteen articles (907 EA patients) met inclusion criteria.; Conclusions: This is the first systematic review aiming to quantify the prevalence of the long-term problems associated with EA. The main active medical conditions (pooled estimated prevalence) identified were the following: dysphagia (50.3%), gastroesophageal reflux disease with (40.2%) or without (56.5%) histological esophagitis, recurrent respiratory tract infections (24.1%), doctor-diagnosed asthma (22.3%), persistent cough (14.6%), and wheeze (34.7%). The prevalence of Barrett's esophagus (6.4%) was 4 and 26 times higher than the adult (1.6%) and pediatric (.25%) general populations. Adult and pediatric practitioners should focus on how to develop effective long-term follow-up and transitional care for these patients.; (Copyright © 2015 Elsevier Inc. All rights reserved.) |
| Contributed Indexing: | Keywords: Barrett’s esophagus; Esophageal atresia; Esophageal cancer; Gastroesophageal reflux; Long-term care; Review |
| Entry Date(s): | Date Created: 20150122 Date Completed: 20150601 Latest Revision: 20250711 |
| Update Code: | 20260130 |
| DOI: | 10.1016/j.amjsurg.2014.09.019 |
| PMID: | 25605033 |
| Database: | MEDLINE |
Journal Article; Meta-Analysis; Systematic Review