Correlation of 2 hour, 4 hour, 8 hour and 12 hour urine protein with 24 hour urinary protein in preeclampsia.
| Title: | Correlation of 2 hour, 4 hour, 8 hour and 12 hour urine protein with 24 hour urinary protein in preeclampsia. |
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| Authors: | Rani Singhal S; Department of Obstetrics and Gynecology, Pt B D Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.; Ghalaut V; Department of Biochemistry, Pt B D Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.; Lata S; Department of Obstetrics and Gynecology, Pt B D Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.; Madaan H; Department of Biochemistry, Pt B D Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.; Kadian V; Department of Obstetrics and Gynecology, Pt B D Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.; Sachdeva A; Department of Biochemistry, Pt B D Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India. |
| Source: | Journal of family & reproductive health [J Family Reprod Health] 2014 Sep; Vol. 8 (3), pp. 131-4. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences Country of Publication: Iran NLM ID: 101496684 Publication Model: Print Cited Medium: Print ISSN: 1735-8949 (Print) Linking ISSN: 17359392 NLM ISO Abbreviation: J Family Reprod Health Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: Tehran : Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences |
| Abstract: | Objective: To find shortest and reliable time period of urine collection for determination of proteinuria.; Materials and Methods: It is a prospective study carried out on 125 pregnant women with preeclampsia after 20 weeks of gestation having urine albumin >1 using dipstick test. Urine was collected in five different time intervals in colors labeled containers with the assistance of nursing staff; the total collection time was 24 hours. Total urine protein of two-hour, four-hour, eight-hour, 12-hour and 24-hour urine was measured and compared with 24-hour collection. Data was analyzed using the Pearson correlation coefficient.; Results: There was significant correlation (p value < 0.01) in two, four, eight and 12-hour urine protein with 24-urine protein, with correlation coefficient of 0.97, 0.97, 0.96 and 0.97, respectively. When a cut off value of 25 mg, 50 mg. 100 mg, and 150 mg for urine protein were used for 2-hour, 4-hours, 8-hour and 12-hour urine collection, a sensitivity of 92.45%, 95.28%, 91.51%, and 96.23% and a specificity of 68.42%, 94.74%, 84.21% and 84.21% were obtained, respectively.; Conclusion: Two-hour urine proteins can be used for assessment of proteinuria in preeclampsia instead of gold standard 24-hour urine collection for early diagnosis and better patient compliance. |
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| Contributed Indexing: | Keywords: Pre Eclampsia; Timed Collection; Urinary Protein |
| Entry Date(s): | Date Created: 20150129 Date Completed: 20150128 Latest Revision: 20231110 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC4275555 |
| PMID: | 25628723 |
| Database: | MEDLINE |
Journal Article