Left ventricular systolic dysfunction in metastatic breast cancer patients: a Polish multicenter registry.
| Title: | Left ventricular systolic dysfunction in metastatic breast cancer patients: a Polish multicenter registry. |
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| Authors: | Szmit S; Department of Pulmonary Circulation and Thromboembolic Diseases, Centre of Postgraduate Medical Education, Otwock, Poland s.szmit@gmail.com.; Streb J; Department of Clinical Oncology, The University Hospital in Cracow, Cracow, Poland.; Starzec W; Department of Oncology, Franciszek Lukaszczyk Oncology Centre in Bydgoszcz, Bydgoszcz, Poland.; Zuziak D; Department of Diagnosis and Treatment of Breast Cancer, Beskid Oncology Centre in Bielsko-Biała, Bielsko-Biała, Poland.; Kwiatkowski M; Department of Oncology, Franciszek Lukaszczyk Oncology Centre in Bydgoszcz, Bydgoszcz, Poland.; Czartoryska-Arłukowicz B; Department of Oncology, Medical University of Białystok, Białystok, Poland.; Iżycki D; Department of Cancer Immunology, Poznan University of Medical Sciences, Poznań, Poland.; Śmiałowska-Janiszewska A; Chemotherapy Department, Regional Center of Oncology in Lodz, Łódź, Poland.; Hanslik J; District Hospital Department of Chemotherapy in Racibórz, Racibórz, Poland.; Bryjak A; Chemotherapy Department, Regional Center of Oncology in Lodz, Łódź, Poland.; Talerczyk M; West Pomeranian Oncology Center in Szczecin, Szczecin, Poland.; Zaucha JM; Department of Oncology and Propedeutic Oncology, Gdynia Oncology Center and Medical University of Gdansk, Gdynia, Poland. |
| Source: | Anticancer research [Anticancer Res] 2015 Feb; Vol. 35 (2), pp. 989-95. |
| Publication Type: | Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
| Language: | English |
| Journal Info: | Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8102988 Publication Model: Print Cited Medium: Internet ISSN: 1791-7530 (Electronic) Linking ISSN: 02507005 NLM ISO Abbreviation: Anticancer Res Subsets: MEDLINE |
| Imprint Name(s): | Publication: Attiki, Greece : International Institute of Anticancer Research; Original Publication: Athens, Greece : Potamitis Press |
| MeSH Terms: | Registries* ; Systole* ; Ventricular Dysfunction, Left*; Breast Neoplasms/*physiopathology ; Neoplasm Metastasis/*physiopathology; Aged ; Female ; Humans ; Middle Aged ; Poland |
| Abstract: | Background: The knowledge of the epidemiology of left ventricular systolic dysfunction (LVSD) in relationship with cardiovascular diseases, their risk factors and history of previous anticancer therapy may lead to development of safer and more effective therapeutic strategies in patients with breast cancer (BC).; Patients and Methods: Oncologists from various Polish Centers reported 299 new cases of metastatic BC requiring chemotherapy. All registered previous cardiological and oncological therapies should be conducted in accordance with the mandatory guidelines.; Results: Twelve new cases (4%) of LVSD were recognized in echocardiography before current chemotherapy. Multivariate logistic regression analysis revealed a significant association of LVSD with hypercholesterolemia (odds ratio (OR)=8.83; 95% confidence interval (CI)=1.44-54.16; p |
| Contributed Indexing: | Keywords: Anthracyclines; chemotherapy; left ventricular systolic dysfunction; metastatic breast cancer; risk factors |
| Entry Date(s): | Date Created: 20150211 Date Completed: 20150409 Latest Revision: 20150210 |
| Update Code: | 20260130 |
| PMID: | 25667486 |
| Database: | MEDLINE |
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't