Drug-eluting stents with biodegradable polymer for the treatment of patients with diabetes mellitus: clinical outcome at 2 years in a large population of patients.
| Title: | Drug-eluting stents with biodegradable polymer for the treatment of patients with diabetes mellitus: clinical outcome at 2 years in a large population of patients. |
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| Authors: | Wiemer M; Department of Cardiology, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.; Danzi GB; Ospedale Maggiore Policlinico, Milan, Italy.; West N; Papworth Hospital, Cambridge, UK.; Voudris V; Onassis Cardiac Surgery Center, Athens, Greece.; Koning R; Clinique Saint Hilaire, Rouen, France.; Hoffmann S; Vivantes Netzwerk für Gesundheit GmbH, Berlin, Germany.; Lombardi M; Azienda Ospedaliera Villa Sofia, Palermo, Italy.; Mauri J; Hospital Universitari Germans Trias i Pujol, Badalona, Spain.; Babic R; Institute for Cardiovascular Diseases Dedinje, Belgrade, Serbia.; Witherow F; Dorset County Hospital, Dorchester, UK. |
| Source: | Medical devices (Auckland, N.Z.) [Med Devices (Auckl)] 2015 Feb 18; Vol. 8, pp. 153-60. Date of Electronic Publication: 2015 Feb 18 (Print Publication: 2015). |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Dove Medical Press Country of Publication: New Zealand NLM ID: 101566041 Publication Model: eCollection Cited Medium: Print ISSN: 1179-1470 (Print) Linking ISSN: 11791470 NLM ISO Abbreviation: Med Devices (Auckl) Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: [Auckland, N.Z.] : Dove Medical Press |
| Abstract: | Objective: This study investigates the safety and efficacy of a third-generation drug-eluting stent (DES) with biodegradable polymer in the complex patient population of diabetes mellitus (DM).; Clinical Trial Registration: ISRCTN81649913.; Background: Percutaneous coronary interventions in patients with DM are associated with a higher incidence of death, restenosis, and stent thrombosis as compared to non-diabetic patients. The use of a DES has been shown to improve outcomes in diabetic patients.; Methods: Out of 3,067 patients, enrolled in 126 centers worldwide in the NOBORI 2 registry, 888 patients suffered from DM, 213 of them (14%) being insulin-dependent DM (IDDM). Two years' follow-up has been completed in this study.; Results: At 1- and 2-year follow-up, 97% and 95% of the patients, respectively, were available. The reported target lesion failure (TLF) rates at 1- and 2-year follow-up were 6.0% and 7.2% in the DM group, respectively, and 3.0% and 4.2% in the non-DM group, respectively (P |
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| Contributed Indexing: | Keywords: biodegradable polymer; diabetes mellitus; drug-eluting stents; percutaneous coronary intervention |
| Entry Date(s): | Date Created: 20150305 Date Completed: 20150304 Latest Revision: 20201001 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC4342370 |
| DOI: | 10.2147/MDER.S67399 |
| PMID: | 25737640 |
| Database: | MEDLINE |
Journal Article