Sleep apnoea and unscheduled re-admission in patients undergoing coronary artery bypass surgery.
| Title: | Sleep apnoea and unscheduled re-admission in patients undergoing coronary artery bypass surgery. |
|---|---|
| Authors: | Zhao LP; Department of Cardiology, National University Heart Centre Singapore, Singapore.; Kofidis T; Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Cardiac, Thoracic and Vascular Surgery, National University Heart Centre Singapore, Singapore.; Chan SP; Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Cardiovascular Research Institute, National University Heart Centre Singapore, Singapore; Department of Mathematics and Statistics, La Trobe University, Australia.; Ong TH; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.; Yeo TC; Department of Cardiology, National University Heart Centre Singapore, Singapore.; Tan HC; Department of Cardiology, National University Heart Centre Singapore, Singapore.; Lee CH; Department of Cardiology, National University Heart Centre Singapore, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address: mdclchr@nus.edu.sg. |
| Source: | Atherosclerosis [Atherosclerosis] 2015 Sep; Vol. 242 (1), pp. 128-34. Date of Electronic Publication: 2015 Jul 10. |
| Publication Type: | Journal Article; Observational Study; Research Support, Non-U.S. Gov't |
| Language: | English |
| Journal Info: | Publisher: Elsevier Country of Publication: Ireland NLM ID: 0242543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1484 (Electronic) Linking ISSN: 00219150 NLM ISO Abbreviation: Atherosclerosis Subsets: MEDLINE |
| Imprint Name(s): | Publication: Limerick : Elsevier; Original Publication: Amsterdam, Elsevier. |
| MeSH Terms: | Coronary Artery Bypass*; Cardiovascular Diseases/*epidemiology ; Coronary Disease/*surgery ; Patient Readmission/*statistics & numerical data ; Postoperative Complications/*epidemiology ; Sleep Apnea Syndromes/*epidemiology; Coronary Disease/epidemiology ; Hypertension/epidemiology ; Kidney Failure, Chronic/epidemiology ; Obesity/epidemiology ; Sleep Apnea Syndromes/diagnosis ; Smoking/epidemiology ; Aged ; Comorbidity ; Disease-Free Survival ; Early Diagnosis ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Polysomnography ; Proportional Hazards Models ; Prospective Studies ; Risk Factors ; Treatment Outcome |
| Abstract: | Introduction: Although it has been recognised as a cardiovascular risk factor, data on sleep apnoea screening before coronary artery bypass grafting (CABG) are scarce. This study sought to determine the prevalence, predictors and effects of sleep apnoea on re-admission in patients undergoing CABG.; Method: We prospectively recruited 152 patients to undergo an overnight sleep study before CABG. Sleep apnoea was defined as an apnoea-hypopnoea index of ≥15 events per hour. Data on unscheduled re-admission due to cardiovascular events were collected.; Results: Among the 138 patients who completed the sleep study, sleep apnoea was diagnosed in 69 (50%). The patients who had sleep apnoea had a lower left ventricular ejection fraction (p = 0.029), a larger left atrial diameter (p = 0.014) and a larger left ventricular end-systolic dimension (p = 0.019) than those who did not. Angiographic SYNTAX and Gensini scores were similar in patients with and without sleep apnoea. The generalised structural equation model revealed that hypertension, a high body mass index and chronic renal failure were independent predictors of sleep apnoea (p < 0.05). After an average follow-up of 6 ± 3 months, 12 patients with sleep apnoea (17.3%) and three patients without sleep apnoea (4.3%) were involved in unscheduled re-admission. Patients with sleep apnoea were almost five times more likely to have an unscheduled re-admission due to cardiovascular events (adjusted odds ratio: 4.63, 95% CI: 1.24-17.31, p = 0.023) than those without sleep apnoea.; Conclusions: Sleep apnoea was prevalent and predictive of unscheduled re-admissions in patients scheduled for CABG.; (Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.) |
| Contributed Indexing: | Keywords: Cardiovascular; Outcomes; Portable; Re-admission; Screening |
| Entry Date(s): | Date Created: 20150720 Date Completed: 20160609 Latest Revision: 20150822 |
| Update Code: | 20260130 |
| DOI: | 10.1016/j.atherosclerosis.2015.07.006 |
| PMID: | 26188535 |
| Database: | MEDLINE |
Journal Article; Observational Study; Research Support, Non-U.S. Gov't