Lymph node retrieval for colorectal cancer: Estimation of the minimum resection length to achieve at least 12 lymph nodes for the pathological analysis.
| Title: | Lymph node retrieval for colorectal cancer: Estimation of the minimum resection length to achieve at least 12 lymph nodes for the pathological analysis. |
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| Authors: | Gravante G; Department of Surgery, Kettering General Hospital, Kettering, United Kingdom.; Parker R; Department of Surgery, Kettering General Hospital, Kettering, United Kingdom.; Elshaer M; Department of Surgery, West Hertfordshire Hospitals, Watford, United Kingdom. Electronic address: mohamedelshaer_1@hotmail.com.; Mogekwu AC; Department of Surgery, Kettering General Hospital, Kettering, United Kingdom.; Humayun N; Department of Surgery, Kettering General Hospital, Kettering, United Kingdom.; Thomas K; Department of Surgery, Kettering General Hospital, Kettering, United Kingdom.; Thomson R; Department of Surgery, Kettering General Hospital, Kettering, United Kingdom.; Hudson S; Department of Surgery, Kettering General Hospital, Kettering, United Kingdom.; Sorge R; Department of Human Physiology, Laboratory of Biometry, University of Tor Vergata, Rome, Italy.; Gardiner K; Department of Surgery, Kettering General Hospital, Kettering, United Kingdom.; Al-Hamali S; Department of Surgery, Kettering General Hospital, Kettering, United Kingdom.; Rashed M; Department of Surgery, Kettering General Hospital, Kettering, United Kingdom.; Kelkar A; Department of Surgery, Kettering General Hospital, Kettering, United Kingdom.; El-Rabaa S; Department of Surgery, Kettering General Hospital, Kettering, United Kingdom. |
| Source: | International journal of surgery (London, England) [Int J Surg] 2016 Jan; Vol. 25, pp. 153-7. Date of Electronic Publication: 2015 Dec 20. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101228232 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1743-9159 (Electronic) Linking ISSN: 17439159 NLM ISO Abbreviation: Int J Surg Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2023- : [Philadelphia] : Wolters Kluwer Health, Inc.; Original Publication: London : Surgical Associates Ltd., c2004- |
| MeSH Terms: | Colectomy/*methods ; Colon/*pathology ; Colorectal Neoplasms/*surgery ; Lymph Node Excision/*standards ; Lymph Nodes/*pathology; Colorectal Neoplasms/pathology ; Lymph Node Excision/methods ; Lymph Nodes/surgery ; Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Organ Size ; Retrospective Studies |
| Abstract: | Introduction: Adequate lymph node retrieval is important in colorectal cancer staging for the selection of patients that necessitate adjuvant treatments. The minimum number of 12 lymph nodes is one of the premises and is dependent, among the other factors, from the length of bowel resected. We have reviewed our specimens to identify the high-risk operations for inadequate nodal sampling and estimate the minimum length of bowel needed to resect to achieve this purpose.; Materials and Methods: A retrospective review of colorectal specimens over 10 years of activity looking at data including location of the tumor, type of operation performed, length of bowel resected and number of lymph nodes retrieved.; Results: Abdominoperineal and Hartmann's resections produced significant lower adequate retrievals compared to other colorectal operations, corresponding to 45.4% and 59.1% of cases respectively. The measured average length of bowel was 30 cm and 25 cm respectively, increasing the length to 36 cm and 42 cm would increase the adequacy rate to 90%.; Conclusions: Abdominoperineal and Hartmann's resections are, in our series, high-risk operations that frequently do not produce the minimum number of lymph nodes necessary. These operations may require additional maneuvers such as mobilization of the splenic flexure to achieve the minimum length of bowel to resect.; (Copyright © 2015 IJS Publishing Group Limited. Published by Elsevier Ltd. All rights reserved.) |
| Contributed Indexing: | Keywords: Abdominoperineal resection; Colorectal cancer; Hartmann resection; Lymph node; Staging |
| Entry Date(s): | Date Created: 20151230 Date Completed: 20160930 Latest Revision: 20181202 |
| Update Code: | 20260130 |
| DOI: | 10.1016/j.ijsu.2015.12.062 |
| PMID: | 26713777 |
| Database: | MEDLINE |
Journal Article