Vena cava compression syndrome in patients with obesity presenting with edema and thrombosis.
| Title: | Vena cava compression syndrome in patients with obesity presenting with edema and thrombosis. |
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| Authors: | Linicus Y; Klinik für Kardiologie, Angiologie und internistische Intensivmedizin, Universität des Saarlandes und Universitätsklinikum des Saarlandes, Homburg, Germany.; Kindermann I; Klinik für Kardiologie, Angiologie und internistische Intensivmedizin, Universität des Saarlandes und Universitätsklinikum des Saarlandes, Homburg, Germany.; Cremers B; Klinik für Kardiologie, Angiologie und internistische Intensivmedizin, Universität des Saarlandes und Universitätsklinikum des Saarlandes, Homburg, Germany.; Maack C; Klinik für Kardiologie, Angiologie und internistische Intensivmedizin, Universität des Saarlandes und Universitätsklinikum des Saarlandes, Homburg, Germany.; Schirmer S; Klinik für Kardiologie, Angiologie und internistische Intensivmedizin, Universität des Saarlandes und Universitätsklinikum des Saarlandes, Homburg, Germany.; Böhm M; Klinik für Kardiologie, Angiologie und internistische Intensivmedizin, Universität des Saarlandes und Universitätsklinikum des Saarlandes, Homburg, Germany. |
| Source: | Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2016 Aug; Vol. 24 (8), pp. 1648-52. Date of Electronic Publication: 2016 Jun 17. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101264860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1930-739X (Electronic) Linking ISSN: 19307381 NLM ISO Abbreviation: Obesity (Silver Spring) Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2013- : Malden, MA : John Wiley & Sons; Original Publication: Silver Spring, MD : NAASO, the Obesity Society, c2006- |
| MeSH Terms: | Central Venous Pressure*; Edema/*etiology ; Obesity/*complications ; Thrombosis/*etiology ; Vena Cava, Inferior/*physiology ; Vena Cava, Inferior/*physiopathology; Adult ; Atrial Function, Right ; Cardiac Catheterization ; Female ; Humans ; Male ; Pressure |
| Abstract: | Objective: Obesity is a risk factor for cardiovascular disease and venous thrombosis. Previous studies have shown that in late pregnancy a compression of the inferior vena cava (VCI) leads to a hypotensive syndrome. The objective of this study was to explore the correlation between obesity and an elevated pressure in the VCI simulating obesity-induced vena cava compression syndrome.; Methods: A left and right heart catheterization was performed in 29 patients. After right atrial pressure measurement, the catheter was pulled back through the VCI, and the pressure gradient between the thoracic and abdominal vena cava was measured. We determined the correlation between the BMI and the pressure gradient.; Results: In 29 patients, a high BMI was associated with an increased pressure gradient between the thoracic and abdominal vena cava (r = 0.66). This correlation was particularly close in patients with a BMI >30 kg/m(2) (P = 0.0008). Two patients had complications such as recurrent thrombosis, with one of them having the highest pressure gradient of 16 mm Hg.; Conclusions: Because mechanical obstruction of the VCI leads to an increased risk for venous thrombosis in patients with obesity, this finding needs to be considered in the decision-making for interventional treatments like bariatric surgery.; (© 2016 The Obesity Society.) |
| Entry Date(s): | Date Created: 20160618 Date Completed: 20170707 Latest Revision: 20181202 |
| Update Code: | 20260130 |
| DOI: | 10.1002/oby.21506 |
| PMID: | 27312050 |
| Database: | MEDLINE |
Journal Article