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Comparison of Long-Term Mortality of Patients Aged ≤40 Versus >40 Years With Acute Myocardial Infarction.

Title: Comparison of Long-Term Mortality of Patients Aged ≤40 Versus >40 Years With Acute Myocardial Infarction.
Authors: Jing M; National University Heart Centre, National University of Singapore, Singapore, Singapore.; Gao F; Department of Cardiology, National Heart Centre, Singapore, Singapore; Center for Quantitative Medicine, Duke-NUS Graduate Medical School, Singapore, Singapore.; Chen Q; Department of Cardiology, National Heart Centre, Singapore, Singapore.; de Carvalho LP; National University Heart Centre, National University of Singapore, Singapore, Singapore.; Sim LL; Department of Cardiology, National Heart Centre, Singapore, Singapore.; Koh TH; Department of Cardiology, National Heart Centre, Singapore, Singapore.; Foo D; Department of Cardiology, Tan Tock Seng Hospital, Singapore, Singapore.; Ong HY; Department of Cardiology, Khoo Teck Puat Hospital, Singapore, Singapore.; Tong KL; Department of Cardiology, Changi General Hospital, Singapore, Singapore.; Tan HC; National University Heart Centre, National University of Singapore, Singapore, Singapore.; Yeo TC; National University Heart Centre, National University of Singapore, Singapore, Singapore.; Roe MT; Duke Clinical Research Institute, Durham, North Carolina.; Chua T; Department of Cardiology, National Heart Centre, Singapore, Singapore.; Chan MY; National University Heart Centre, National University of Singapore, Singapore, Singapore. Electronic address: mark_chan@nuhs.edu.sg.
Source: The American journal of cardiology [Am J Cardiol] 2016 Aug 01; Vol. 118 (3), pp. 319-25. Date of Electronic Publication: 2016 May 14.
Publication Type: Comparative Study; Journal Article
Language: English
Journal Info: Publisher: Excerpta Medica Country of Publication: United States NLM ID: 0207277 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1913 (Electronic) Linking ISSN: 00029149 NLM ISO Abbreviation: Am J Cardiol Subsets: MEDLINE
Imprint Name(s): Original Publication: New York, NY : Excerpta Medica
MeSH Terms: Registries* ; Survival Rate*; Cardiovascular Diseases/*mortality ; Myocardial Infarction/*epidemiology; Adult ; Age Factors ; Aged ; Cause of Death ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Mortality ; Prognosis ; Proportional Hazards Models ; Singapore
Abstract: Young patients with acute myocardial infarction (MI) have a more favorable prognosis than older patients with MI. However, there are limited data comparing the prognosis of young patients with MI with young population controls. Comparison with an age-matched background population could unmask residual mortality risk in young patients with MI that would otherwise not be apparent when merely comparing the mortality risk of young and older patients with MI. We studied 15,151 patients with AMI from 2000 to 2005, of which 601 patients were ≤40 years (young MI). The relative survival ratio (RSR) was calculated as the ratio of the observed survival of patients with MI divided by the expected survival, estimated from the background population (n = 3,771,700) matched for age, gender, and follow-up year. An RSR of 1.0 indicates poorer or better survival, respectively, than the background population. The 12-year all-cause and cardiovascular mortality of young versus older patients was 12.8% versus 50.7% (p
Entry Date(s): Date Created: 20160623 Date Completed: 20170501 Latest Revision: 20260127
Update Code: 20260130
DOI: 10.1016/j.amjcard.2016.05.002
PMID: 27328956
Database: MEDLINE

Comparative Study; Journal Article