Evaluation of the role of left atrial strain using two-dimensional speckle tracking echocardiography in patients with diabetes mellitus and heart failure with preserved left ventricular ejection fraction.
| Title: | Evaluation of the role of left atrial strain using two-dimensional speckle tracking echocardiography in patients with diabetes mellitus and heart failure with preserved left ventricular ejection fraction. |
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| Authors: | Georgievska-Ismail L; University Clinic of Cardiology, University 'St. Cyril and Methodius', Skopje, Republic of Macedonia lgismail@gmail.com.; Zafirovska P; Special Hospital for Surgical Diseases 'Filip II', Skopje, Republic of Macedonia.; Hristovski Z; Clinical Hospital 'Acibadem Sistina', Skopje, Republic of Macedonia. |
| Source: | Diabetes & vascular disease research [Diab Vasc Dis Res] 2016 Nov; Vol. 13 (6), pp. 384-394. Date of Electronic Publication: 2016 Jul 12. |
| Publication Type: | Evaluation Study; Journal Article |
| Language: | English |
| Journal Info: | Publisher: Sage Publications Country of Publication: England NLM ID: 101234011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8984 (Electronic) Linking ISSN: 14791641 NLM ISO Abbreviation: Diab Vasc Dis Res Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2009- : London : Sage Publications; Original Publication: Edgbaston, Birmingham, UK : Sherborne Gibbs, c2005- |
| MeSH Terms: | Atrial Function, Left* ; Myocardial Contraction* ; Stroke Volume* ; Ventricular Function, Left*; Diabetes Mellitus, Type 2/*complications ; Diabetic Cardiomyopathies/*diagnostic imaging ; Echocardiography, Doppler/*methods ; Heart Failure/*diagnostic imaging; Diabetes Mellitus, Type 2/diagnosis ; Diabetic Cardiomyopathies/etiology ; Diabetic Cardiomyopathies/physiopathology ; Heart Failure/etiology ; Heart Failure/physiopathology ; Aged ; Biomechanical Phenomena ; Chi-Square Distribution ; Cross-Sectional Studies ; Female ; Humans ; Linear Models ; Male ; Middle Aged ; Predictive Value of Tests ; Prospective Studies ; Risk Factors ; Stress, Mechanical |
| Abstract: | Objective: To evaluate additional role of left atrial two-dimensional speckle tracking echocardiography in patients with diabetes mellitus type 2, 218 patients with heart failure with preserved left ventricular ejection fraction divided according to the presence of diabetes mellitus (108 with and 110 without) were enrolled in the study.; Methods: Traditional parameters using two-dimensional echocardiography and Doppler imaging were measured as expressions of left ventricular diastolic function as well as peak atrial longitudinal strain and peak atrial contraction strain were measured using two-dimensional speckle tracking echocardiography.; Results: Global average peak atrial longitudinal strain and peak atrial contraction strain were significantly lower in patients with diabetes mellitus (p = 0.002 and p = 0.001, respectively) and its reduced values were significantly associated with higher prevalence of diabetes mellitus (p = 0.002 and p = 0.001, respectively), its greater severity (p = 0.002 and p = 0.016, respectively) and longer duration only for global average peak atrial longitudinal strain (p = 0.030). Multiple linear regression analysis demonstrated that the presence of diabetes mellitus appeared as independent predictor of reduced global peak atrial longitudinal strain [B = -2.173; 95% confidence interval: -3.870 to (-0.477); p = 0.012] as well of reduced global peak atrial contraction strain [B = -1.30; 95% confidence interval: -2.234 to (-0.366); p = 0.007].; Conclusion: Two-dimensional speckle tracking echocardiography appeared as a useful additional tool for detection of left atrial dysfunction in patients with heart failure who have preserved left ventricular ejection fraction and diabetes mellitus who are especially prone to develop cardiovascular complications.; (© The Author(s) 2016.) |
| Contributed Indexing: | Keywords: Left atrial deformation; diabetes mellitus; heart failure with preserve left ventricular ejection fraction; speckle tracking echocardiography |
| Entry Date(s): | Date Created: 20160714 Date Completed: 20171010 Latest Revision: 20191210 |
| Update Code: | 20260130 |
| DOI: | 10.1177/1479164116655558 |
| PMID: | 27407084 |
| Database: | MEDLINE |
Evaluation Study; Journal Article