Hoarse voice: a rare presentation of tuberculosis lymphadenitis.
| Title: | Hoarse voice: a rare presentation of tuberculosis lymphadenitis. |
|---|---|
| Authors: | Springford LR; Imperial College Healthcare NHS Trust, London, UK.; Department of Ear, Nose and Throat Surgery, Northwick Park Hospital, London, UK.; Ramdoo K; Department of Ear, Nose and Throat Surgery, Northwick Park Hospital, London, UK.; Nair D; Department of Ear, Nose and Throat Surgery, Northwick Park Hospital, London, UK.; Taghi A; Imperial College Healthcare NHS Trust, London, UK.; Department of Ear, Nose and Throat Surgery, Northwick Park Hospital, London, UK. |
| Source: | BMJ case reports [BMJ Case Rep] 2016 Oct 24; Vol. 2016. Date of Electronic Publication: 2016 Oct 24. |
| Publication Type: | Case Reports; Journal Article |
| Language: | English |
| Journal Info: | Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101526291 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-790X (Electronic) Linking ISSN: 1757790X NLM ISO Abbreviation: BMJ Case Rep Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: London : BMJ Pub. Group |
| MeSH Terms: | Hoarseness/*etiology ; Tuberculosis, Lymph Node/*diagnosis; Antitubercular Agents/therapeutic use ; Tuberculosis, Lymph Node/drug therapy ; Adult ; Diagnosis, Differential ; Humans ; Laryngoscopy ; Magnetic Resonance Imaging ; Male ; Polymerase Chain Reaction ; Tomography, X-Ray Computed ; Tuberculin Test |
| Abstract: | A man aged 37 years from Indian descent presented to an inner city London hospital with hoarseness of voice, fatigue, night sweats and a 2 kg weight loss. Laryngoscopy demonstrated a left vocal fold palsy. Extensive investigations were undertaken with disseminated malignancy being primarily investigated. CT/MRI scanning showed non-specific necrotic mediastinal lymph nodes. Tuberculin skin testing, cytology and PCR were eventually undergone. Tests yielded results consistent with tuberculosis (TB) infection and the patient was started on standard TB treatment protocol, with excellent results. TB infection can result in multiple atypical presentations of disease, including hoarseness of voice secondary to vocal cord paralysis. This is a rare but important presentation for community clinician's to consider, especially in populations where TB is epidemiologically thought to be prevalent.; (2016 BMJ Publishing Group Ltd.) |
| Competing Interests: | Conflicts of Interest: None declared. |
| References: | Nepal Med Coll J. 2008 Jun;10(2):141-3. (PMID: 18828442); Ann Thorac Surg. 2000 Dec;70(6):2142-3. (PMID: 11156137); Tuberk Toraks. 2007;55(4):409-13. (PMID: 18224512); BMJ Case Rep. 2011 Oct 11;2011:null. (PMID: 22675007); Jpn J Infect Dis. 2004 Jun;57(3):124-6. (PMID: 15218225) |
| Substance Nomenclature: | 0 (Antitubercular Agents) |
| Entry Date(s): | Date Created: 20161101 Date Completed: 20170223 Latest Revision: 20181113 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC5093793 |
| DOI: | 10.1136/bcr-2016-216022 |
| PMID: | 27797813 |
| Database: | MEDLINE |
Case Reports; Journal Article