The factors affecting survival in patients with bronchiectasis.
| Title: | The factors affecting survival in patients with bronchiectasis. |
|---|---|
| Authors: | Çiftçi F; Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.; Şen E; Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.; Saryal SB; Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.; Önen ZP; Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.; Gülbay B; Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.; Yıldız Ö; Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.; Acıcan T; Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.; Karabıyıkoğlu G; Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey. |
| Source: | Turkish journal of medical sciences [Turk J Med Sci] 2016 Dec 20; Vol. 46 (6), pp. 1838-1845. Date of Electronic Publication: 2016 Dec 20. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Scientific and Technical Research Council of Turkey Country of Publication: Turkey NLM ID: 9441758 Publication Model: Electronic Cited Medium: Print ISSN: 1300-0144 (Print) Linking ISSN: 13000144 NLM ISO Abbreviation: Turk J Med Sci Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Ankara : Scientific and Technical Research Council of Turkey, [1994- |
| MeSH Terms: | Bronchiectasis*; Humans ; Pseudomonas Infections ; Pseudomonas aeruginosa ; Respiratory Function Tests ; Sputum |
| Abstract: | Background/aim: There is limited information about the rate and modifiers of mortality in noncystic fibrosis bronchiectasis.; Materials and Methods: This study enrolled a total of 56 bronchiectasis patients. Patients' body mass index, smoking habit, previous therapies, comorbid disorders, history of vaccination, bronchiectasis type and radiological extent, arterial blood gas analysis, respiratory function tests, and laboratory results were recorded.; Results: After a follow-up of 65.38 ± 18.62 months the overall mortality rate was 35.7%. The mean survival duration was 46.42 ± 8.25 months. Advanced age significantly increased mortality (HR: 2.031; CI: 0.991-4.072, P = 0.035). A significant correlation was found between mortality rate and the partial oxygen pressure level (HR: 0.886 (CI: 0.817-0.960); P = 0.039). Pulmonary artery pressure was directly proportional to mortality rate (HR: 9.015 (CI: 3.272-94.036); P = 0.03). There was also a significant correlation between Pseudomonas aeruginosa proliferation in sputum and mortality (HR: 7.014 (CI: 2.812-17.962); P = 0.00). Comorbidities increased mortality (HR: 1.984 (CI: 0.972-2.996); P = 0.04).; Conclusion: Bronchiectasis is a disease with high mortality. Advanced age, comorbid conditions, reduced partial oxygen pressure, pulmonary hypertension, and Pseudomonas aeruginosa proliferation in sputum increase its mortality rate. |
| Contributed Indexing: | Keywords: Bronchiectasis survival; Pseudomonas aeruginosa; mortality |
| Entry Date(s): | Date Created: 20170113 Date Completed: 20180920 Latest Revision: 20181004 |
| Update Code: | 20260130 |
| DOI: | 10.3906/sag-1511-137 |
| PMID: | 28081336 |
| Database: | MEDLINE |
Journal Article