Comparative analysis of recurrent events after presentation with an index myocardial infarction or ischaemic stroke.
| Title: | Comparative analysis of recurrent events after presentation with an index myocardial infarction or ischaemic stroke. |
|---|---|
| Authors: | Yeo KK; Department of Cardiology, National Heart Centre Singapore, 5 Hospital Drive, Singapore 169609.; Duke-NUS Medical School, 8 College Road, Singapore 169857.; Zheng H; National Registry of Diseases Office, Health Promotion Board, 3 Second Hospital Ave, Singapore 168937.; Chow KY; National Registry of Diseases Office, Health Promotion Board, 3 Second Hospital Ave, Singapore 168937.; Ahmad A; Department of Medicine, Jurong Health, 1 Jurong East Street 21, Singapore 609606.; Chan BPL; Department of Neurology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore 119074.; Chang HM; National Neuroscience Institute, Singapore General Hospital Campus, Outram Road, Singapore 169608.; Chong E; Department of Medicine, Ng Teng Fong Hospital, 1 Jurong East Street 21, Singapore 609606.; Chua TSJ; Department of Cardiology, National Heart Centre Singapore, 5 Hospital Drive, Singapore 169609.; Foo DCG; Department of Cardiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433.; Low LP; Low Cardiology Clinic, Mount Elizabeth Medical Centre, 3 Mount Elizabeth, Singapore 228510.; Ong MEH; Department of Accident & Emergency, Singapore General Hospital, Outram Road, Singapore 169608.; Ong HY; Department of Cardiology, Khoo Teck Puat Hospital, 90 Yishun Central, Singapore 768828.; Koh TH; Department of Cardiology, National Heart Centre Singapore, 5 Hospital Drive, Singapore 169609.; Tan HC; National University Heart Centre, National University Health System, Singapore 5 Lower Kent Ridge Rd, Singapore 119074.; Tang KF; Tang Neurology & Medical Clinic, Mount Elizabeth Medical Centre, 3 Mount Elizabeth, Singapore 228510.; Venketasubramanian N; Raffles Neuroscience Centre, Raffles Hospital, 585 North Bridge Road, Singapore 188770. |
| Source: | European heart journal. Quality of care & clinical outcomes [Eur Heart J Qual Care Clin Outcomes] 2017 Jul 01; Vol. 3 (3), pp. 234-242. |
| Publication Type: | Comparative Study; Journal Article; Multicenter Study |
| Language: | English |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 101677796 Publication Model: Print Cited Medium: Internet ISSN: 2058-1742 (Electronic) Linking ISSN: 20581742 NLM ISO Abbreviation: Eur Heart J Qual Care Clin Outcomes Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Oxford : Oxford University Press, [2015]- |
| MeSH Terms: | Registries*; Myocardial Infarction/*epidemiology ; Stroke/*epidemiology; Cause of Death/trends ; Morbidity/trends ; Singapore/epidemiology ; Survival Rate/trends ; Aged ; Female ; Humans ; Male ; Recurrence ; Retrospective Studies ; Risk Factors |
| Abstract: | Aims: Acute myocardial infarction (AMI) and stroke are important causes of mortality and morbidity. Our aims are to determine the comparative epidemiology of AMI and ischaemic stroke; and examine the differences in cardiovascular outcomes or mortality occurring after an AMI or stroke.; Methods and Results: The Singapore National Registry of Diseases Office collects countrywide data on AMI, stroke, and mortality. Index events of AMI and ischaemic stroke between 2007 and 2012 were identified. Patients were then matched for occurrences of subsequent AMI, stroke, or death within 1-year of the index event. There were 33 222 patients with first-ever AMI and 20 982 with first-ever stroke. AMI patients were significantly more likely to be men (66.3% vs. 56.9%), non-Chinese (32.1% vs. 24.1%), and smokers (43.1% vs. 38.6%), but less likely to have hypertension (65.6% vs. 79%) and hyperlipidaemia (61.1% vs. 65.5%), compared with stroke patients. In total 6.8% of the AMI patients had recurrent AMI, whereas 4.8% of the stroke patients had recurrent stroke within 1 year; 31.7% of the AMI patients died, whereas 17.1% of the ischaemic stroke patients died within 1 year. Older age, Malay ethnicity, and diabetes mellitus were statistically significant risk factors for all-cause mortality and for the composite endpoint of AMI, stroke, and all-cause mortality, at 1 year.; Conclusions: Risk profiles of patients with AMI and stroke are significantly different. Patients suffer recurrent events in vascular territories similar to the index event. Age and diabetes mellitus are significant predictors of recurrent vascular events and mortality.; (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For Permissions, please email: journals.permissions@oup.com.) |
| Contributed Indexing: | Keywords: Epidemiology; Myocardial infarction; Stroke |
| Entry Date(s): | Date Created: 20170826 Date Completed: 20181031 Latest Revision: 20260127 |
| Update Code: | 20260130 |
| DOI: | 10.1093/ehjqcco/qcw048 |
| PMID: | 28838084 |
| Database: | MEDLINE |
Comparative Study; Journal Article; Multicenter Study