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Improvement in Exophiala dermatitidis airway persistence and respiratory decline in response to interferon-gamma therapy in a patient with cystic fibrosis.

Title: Improvement in Exophiala dermatitidis airway persistence and respiratory decline in response to interferon-gamma therapy in a patient with cystic fibrosis.
Authors: Eades CP; Department of Clinical Infection, Chelsea and Westminster NHS Foundation Trust, London, UK; Department of Infection and Immunity, North West London Pathology NHS Trusts London, UK. Electronic address: Christopher.eades@nhs.net.; Armstrong-James DPH; National Heart and Lung Institute, Imperial College London, UK; Department of Respiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, UK.; Periselneris J; National Heart and Lung Institute, Imperial College London, UK; Department of Respiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, UK.; Jones A; Department of Respiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, UK.; Simmonds N; Department of Respiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, UK.; Kelleher P; Department of Infection and Immunity, North West London Pathology NHS Trusts London, UK; Department of Respiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, UK; Centre for Immunology & Vaccinology, Department of Medicine, Imperial College London, UK.; Shah A; National Heart and Lung Institute, Imperial College London, UK; Department of Respiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, UK.
Source: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2018 May; Vol. 17 (3), pp. e32-e34. Date of Electronic Publication: 2018 Feb 15.
Publication Type: Case Reports; Journal Article
Language: English
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101128966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5010 (Electronic) Linking ISSN: 15691993 NLM ISO Abbreviation: J Cyst Fibros Subsets: MEDLINE
Imprint Name(s): Original Publication: Amsterdam ; New York : Elsevier, c2002-
MeSH Terms: Cystic Fibrosis*/complications ; Cystic Fibrosis*/immunology ; Cystic Fibrosis*/microbiology ; Cystic Fibrosis*/therapy ; Exophiala*/drug effects ; Exophiala*/isolation & purification ; Interferon-gamma*/administration & dosage ; Interferon-gamma*/immunology ; Lung Diseases, Fungal*/drug therapy ; Lung Diseases, Fungal*/etiology ; Lung Diseases, Fungal*/microbiology ; Lung Diseases, Fungal*/physiopathology; Amphotericin B/*adverse effects ; Nitriles/*adverse effects ; Pyridines/*adverse effects ; Triazoles/*adverse effects; Amphotericin B/administration & dosage ; Antifungal Agents/administration & dosage ; Antifungal Agents/adverse effects ; Interleukin-17/immunology ; Monitoring, Immunologic/methods ; Nitriles/administration & dosage ; Pyridines/administration & dosage ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/immunology ; Respiratory Function Tests/methods ; Sputum/microbiology ; Triazoles/administration & dosage ; Disease Progression ; Humans ; Male ; Treatment Outcome ; Young Adult
Grant Information: G0902260 United Kingdom MRC_ Medical Research Council
Contributed Indexing: Keywords: Cystic fibrosis; Fungal; Immunology; Lung
Substance Nomenclature: 0 (Antifungal Agents); 0 (Interleukin-17); 0 (Nitriles); 0 (Pyridines); 0 (Recombinant Proteins); 0 (Triazoles); 21K6M2I7AG (interferon gamma-1b); 60UTO373KE (isavuconazole); 7XU7A7DROE (Amphotericin B); 82115-62-6 (Interferon-gamma)
Entry Date(s): Date Created: 20180220 Date Completed: 20191125 Latest Revision: 20250530
Update Code: 20260130
DOI: 10.1016/j.jcf.2018.02.002
PMID: 29456196
Database: MEDLINE

Case Reports; Journal Article