The Comparison of the Effect of Mannitol and N Acetyl Cysteine on Liver Function in Partial Hepatectomy.
| Title: | The Comparison of the Effect of Mannitol and N Acetyl Cysteine on Liver Function in Partial Hepatectomy. |
|---|---|
| Authors: | Janatmakan F; Department of Anesthesia, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.; Javaherforoosh Zadeh F; Department of Anesthesia, Ahvaz Anesthesiology and Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.; Alizadeh M; Department of Anesthesia, Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.; Alizadeh Z; Department of Anesthesia, Pain Research Center, Yasouj University of Medical Sciences, Yasouj, Iran.; Bahreini A; Department of Surgery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. |
| Source: | Anesthesiology and pain medicine [Anesth Pain Med] 2018 Sep 22; Vol. 8 (5), pp. e79677. Date of Electronic Publication: 2018 Sep 22 (Print Publication: 2018). |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Brieflands Country of Publication: Netherlands NLM ID: 101585412 Publication Model: eCollection Cited Medium: Print ISSN: 2228-7523 (Print) Linking ISSN: 22287523 NLM ISO Abbreviation: Anesth Pain Med Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Publication: 's-Hertogenbosch, The Netherlands : Brieflands; Original Publication: Hoensbroek, Limburg : Kowsar Corp. |
| Abstract: | The alterations in liver function in patients after major liver resection are complex. Partial hepatectomy surgery is considered as a selective therapeutic approach in many benign and malignant liver tumors, secondary metastases, and liver trauma. According to surgical techniques most often based on vascular control and hepatic venous closure (Pringle maneuver), related complications such as ischemia and decreased venous return during and after surgery can be seen. In this study, the effects of Mannitol and N-acetylcysteine, on liver function, after hepatectomy surgery, were compared. This study was shown that infusion N-acetylcysteine next to mannitol, in partial hepatectomy surgeries, was not the significant difference to improve liver function, hemodynamic status, and laboratory tests. |
| Competing Interests: | Conflict of Interests:Authors of this manuscript have no conflict of interests. |
| References: | Anesthesiol Clin. 2015 Mar;33(1):125-41. (PMID: 25701932); ANZ J Surg. 2018 Jun;88(6):E486-E490. (PMID: 29132195); J Clin Transl Hepatol. 2018 Mar 28;6(1):97-104. (PMID: 29577036); J Surg Oncol. 2016 Sep;114(4):446-50. (PMID: 27302646); J Pediatr Surg. 2004 Aug;39(8):1226-9. (PMID: 15300532); Liver Transpl. 2008 Jan;14(1):25-30. (PMID: 18161828) |
| Contributed Indexing: | Keywords: Liver Function; Mannitol; N-acetylcysteine; Partial Hepatectomy |
| Entry Date(s): | Date Created: 20181212 Latest Revision: 20200930 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC6240830 |
| DOI: | 10.5812/aapm.79677 |
| PMID: | 30533390 |
| Database: | MEDLINE |
Journal Article