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Neurotoxicity of Nanomaterials: An Up-to-Date Overview.

Title: Neurotoxicity of Nanomaterials: An Up-to-Date Overview.
Authors: Teleanu DM; Emergency University Hospital, Bucharest, Romania, 'Carol Davila' University of Medicine and Pharmacy, Bucharest 050474, Romania. telepapa@hotmail.com.; Chircov C; Faculty of Engineering in Foreign Languages, Politehnica University of Bucharest, București 060042, Romania. cristina.chircov@yahoo.com.; Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, Bucharest 060041, Romania. cristina.chircov@yahoo.com.; Grumezescu AM; Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, Bucharest 060041, Romania. grumezescu@yahoo.com.; ICUB-Research Institute of University of Bucharest, University of Bucharest, 36-46 M. Kogalniceanu Blvd., Bucharest 050107, Romania. grumezescu@yahoo.com.; Teleanu RI; Emergency University Hospital, Bucharest, Romania, 'Carol Davila' University of Medicine and Pharmacy, Bucharest 050474, Romania. raluca.teleanu@umfcd.ro.
Source: Nanomaterials (Basel, Switzerland) [Nanomaterials (Basel)] 2019 Jan 13; Vol. 9 (1). Date of Electronic Publication: 2019 Jan 13.
Publication Type: Journal Article; Review
Language: English
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101610216 Publication Model: Electronic Cited Medium: Print ISSN: 2079-4991 (Print) Linking ISSN: 20794991 NLM ISO Abbreviation: Nanomaterials (Basel) Subsets: PubMed not MEDLINE
Imprint Name(s): Original Publication: Basel, Switzerland : MDPI AG, [2011]-
Abstract: The field of nanotechnology, through which nanomaterials are designed, characterized, produced, and applied, is rapidly emerging in various fields, including energy, electronics, food and agriculture, environmental science, cosmetics, and medicine. The most common biomedical applications of nanomaterials involve drug delivery, bioimaging, and gene and cancer therapy. Since they possess unique properties which are different than bulk materials, toxic effects and long-term impacts on organisms are not completely known. Therefore, the purpose of this review is to emphasize the main neurotoxic effects induced by nanoparticles, liposomes, dendrimers, carbon nanotubes, and quantum dots, as well as the key neurotoxicology assays to evaluate them.
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Contributed Indexing: Keywords: bioimaging; cancer therapy; drug delivery; gene therapy; nanomaterials; neurotoxicity
Entry Date(s): Date Created: 20190116 Latest Revision: 20201001
Update Code: 20260130
PubMed Central ID: PMC6359621
DOI: 10.3390/nano9010096
PMID: 30642104
Database: MEDLINE

Journal Article; Review