Successful Psoriasis Treatment Using NB-UVB with Methotrexate: The Vietnamese Experience.
| Title: | Successful Psoriasis Treatment Using NB-UVB with Methotrexate: The Vietnamese Experience. |
|---|---|
| Authors: | Van ED; 108 Institute of Clinical Medicine and Pharmaceutical Sciences, Hanoi, Vietnam.; Diem TP; Kien Giang General Hospital, Rach Gia, Vietnam.; Thi VB; 108 Institute of Clinical Medicine and Pharmaceutical Sciences, Hanoi, Vietnam.; Xuan THT; Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.; Tuan KL; 108 Institute of Clinical Medicine and Pharmaceutical Sciences, Hanoi, Vietnam.; Quynh TN; 108 Institute of Clinical Medicine and Pharmaceutical Sciences, Hanoi, Vietnam.; Thu TV; 108 Institute of Clinical Medicine and Pharmaceutical Sciences, Hanoi, Vietnam.; Van TN; National Hospital of Dermatology and Venereology, Hanoi, Vietnam.; Huu SN; National Hospital of Dermatology and Venereology, Hanoi, Vietnam.; Minh PPT; National Hospital of Dermatology and Venereology, Hanoi, Vietnam.; Huu ND; National Hospital of Dermatology and Venereology, Hanoi, Vietnam.; Van TH; National Hospital of Dermatology and Venereology, Hanoi, Vietnam.; Hau KT; National Hospital of Dermatology and Venereology, Hanoi, Vietnam.; Gandolfi M; Unit of Dermatology, University of Parma, Parma, Italy.; Satolli F; Unit of Dermatology, University of Parma, Parma, Italy.; Feliciani C; Unit of Dermatology, University of Parma, Parma, Italy.; Tirant M; University of Rome G. Marconi, Rome, Italy.; Psoriasis Eczema Clinic, Melbourne, Australia.; Vojvodic A; Department of Dermatology and Venereology, Military Medical Academy of Belgrade, Belgrade, Serbia.; Lotti T; University of Rome G. Marconi, Rome, Italy. |
| Source: | Open access Macedonian journal of medical sciences [Open Access Maced J Med Sci] 2019 Jan 27; Vol. 7 (2), pp. 253-255. Date of Electronic Publication: 2019 Jan 27 (Print Publication: 2019). |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Scientific Foundation SPIROSKI Country of Publication: North Macedonia NLM ID: 101662294 Publication Model: eCollection Cited Medium: Print ISSN: 1857-9655 (Print) Linking ISSN: 18579655 NLM ISO Abbreviation: Open Access Maced J Med Sci Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Publication: Skopje, Republic of Macedonia : Scientific Foundation SPIROSKI; Original Publication: Skopje, Republic of Macedonia : ID Design Press, [2013]- |
| Abstract: | Aim: To compare the effectiveness of narrowband ultraviolet B (NBUVB) and oral methotrexate (MTX) to oral MTX alone in Vietnamese psoriasis patients, from May 2016 to May 2018.; Methods: We conducted a non-randomized trial on 70 patients with plaque-type psoriasis of moderate to severe. Thirty-five patients apply NBUVB once/day in 5 days/week for 4 weeks plus oral MTX 7.5 mg/week and 35 patients oral MTX 7.5 mg/week and both two groups treatment for 3 months. The extent of the lesion was assessed by the Psoriasis Area and Severity Index (PASI).; Results: The proportion of decreasing PASI was comparable (68.49% in NBUVB and MTX versus 57.62% in MTX alone); p < 0.05. Inside, good 28.58%, moderate 68.57% and poor 2.85% in NBUVB and MTX better than good 2.85%, moderate 71.4% and poor 25.72% in MTX alone; p < 0.05. The recurrence rate after 24 months of the NBUVB and MTX group (42.9%) was lower than the MTX alone group (71.4%); p < 0.05.; Conclusion: NBUVB and oral MTX have affected treatment with chronic plaque psoriasis better than oral MTX alone. |
| References: | J Eur Acad Dermatol Venereol. 2010 May;24(5):595-600. (PMID: 20015056); Photodermatol Photoimmunol Photomed. 2011 Aug;27(4):186-9. (PMID: 21729166); Br J Dermatol. 2012 Jan;166(1):147-53. (PMID: 21910714); J Am Acad Dermatol. 2014 Jul;71(1):141-50. (PMID: 24655820); J Dermatolog Treat. 2015;26(6):528-34. (PMID: 25909368); Open Access Maced J Med Sci. 2018 May 18;6(5):839-842. (PMID: 29875856); Dermatol Ther. 2018 Sep;31(5):e12627. (PMID: 30133906); Dermatol Ther. 2018 Sep 2;:e12624. (PMID: 30175556); J Am Acad Dermatol. 1982 Dec;7(6):758-62. (PMID: 7174914); J Dermatol Sci. 1997 Feb;14(2):145-53. (PMID: 9039978) |
| Contributed Indexing: | Keywords: Methotrexate; Narrowband ultraviolet B; Psoriasis vulgaris |
| Entry Date(s): | Date Created: 20190213 Latest Revision: 20200930 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC6364742 |
| DOI: | 10.3889/oamjms.2019.065 |
| PMID: | 30745973 |
| Database: | MEDLINE |
Journal Article