Rare Complication of Carotid Stenting: New-Onset Refractory Status Epilepticus: A Study of Five Patients.
| Title: | Rare Complication of Carotid Stenting: New-Onset Refractory Status Epilepticus: A Study of Five Patients. |
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| Authors: | Deshmukh ND; Department of Neurology, Bombay Hospital and Institute of Medical Sciences, Mumbai, Maharashtra, India.; Singh RK; Department of Neurology, Bombay Hospital and Institute of Medical Sciences, Mumbai, Maharashtra, India.; Lalla RS; Department of Neurology, Fortis Hospital, Mumbai, Maharashtra, India.; Karapurkar AP; Department of Intervention Neurology and Endovascular Neurosurgery, Breach Candy Trust Hospital, Mumbai, Maharashtra, India.; Khadilkar SV; Department of Neurology, Bombay Hospital and Institute of Medical Sciences, Mumbai, Maharashtra, India. |
| Source: | Annals of Indian Academy of Neurology [Ann Indian Acad Neurol] 2019 Apr-Jun; Vol. 22 (2), pp. 210-212. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Medknow Country of Publication: India NLM ID: 101273955 Publication Model: Print Cited Medium: Print ISSN: 0972-2327 (Print) Linking ISSN: 09722327 NLM ISO Abbreviation: Ann Indian Acad Neurol Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: Mumbai, India : Medknow |
| Abstract: | Introduction: New-onset refractory status epilepticus (NORSE) is uncommon and almost 50% of cases are cryptogenic. We report the rare development of NORSE following carotid artery stenting (CAS), a procedure which is increasingly being used to treat the carotid stenosis.; Materials and Methods: Patients who developed NORSE following CAS for the prevention of stroke over a period of 5 years were analyzed retrospectively. The degree of internal carotid artery stenosis (ICA) was estimated as per the NASCET criteria.; Results: We analyzed five patients (age: 56-83 years). NORSE was reported within 30 min to 14 days post-CAS. Status epilepticus was focal in two patients, generalized in two, and one had nonconvulsive status epilepticus. All patients were treated with multiple antiepileptic drugs. Four patients recovered and survived and one succumbed. Two patients had comorbid hypertension and two had diabetes and hypertension. Four patients had hemiparesis due to the contralateral middle cerebral artery territory infarction and one patient had syncope. Two patients had postinfarction gliosis.; Conclusions: We report a new cause of NORSE, following CAS. Stroke resulting in gliosis and cerebral hyperperfusion syndrome are the proposed mechanisms. |
| Competing Interests: | There are no conflicts of interest. |
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| Contributed Indexing: | Keywords: Carotid artery stenting; cerebral hyperperfusion syndrome; new-onset refractory status epilepticus |
| Entry Date(s): | Date Created: 20190423 Latest Revision: 20220408 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC6472247 |
| DOI: | 10.4103/aian.AIAN_445_18 |
| PMID: | 31007435 |
| Database: | MEDLINE |
Journal Article